Results of the first-in-human study of ABBV-075 (mivebresib), a pan-inhibitor of bromodomain (BD) and extra terminal (BET) proteins, in patients (pts) with relapsed/refractory (R/R) solid tumors.
Piha-Paul S, Sachdev J, Barve M, LoRusso P, Szmulewitz R, Patel S, McKee M, Wolff J, Hu B, Sood A, Chen X, Wilson S, O'Neil B. Results of the first-in-human study of ABBV-075 (mivebresib), a pan-inhibitor of bromodomain (BD) and extra terminal (BET) proteins, in patients (pts) with relapsed/refractory (R/R) solid tumors. Journal Of Clinical Oncology 2018, 36: 2510-2510. DOI: 10.1200/jco.2018.36.15_suppl.2510.Peer-Reviewed Original ResearchGene expression and cytokine modulation in a first in human (FIH) study of a pan BET inhibitor ABBV-075 in solid tumors.
O'Neil B, Modi D, LoRusso P, Wong S, Motwani M, Sachdev J, Wolff J, Patel S, Hu B, Szmulewitz R, Sood A, Barve M, McKee M, Piha-Paul S. Gene expression and cytokine modulation in a first in human (FIH) study of a pan BET inhibitor ABBV-075 in solid tumors. Journal Of Clinical Oncology 2018, 36: 2570-2570. DOI: 10.1200/jco.2018.36.15_suppl.2570.Peer-Reviewed Original Research