2001
Development of Layer I Neurons in the Primate Cerebral Cortex
Zecevic N, Rakic P. Development of Layer I Neurons in the Primate Cerebral Cortex. Journal Of Neuroscience 2001, 21: 5607-5619. PMID: 11466432, PMCID: PMC6762645, DOI: 10.1523/jneurosci.21-15-05607.2001.Peer-Reviewed Original ResearchConceptsCerebral cortexLayer ILayer I cellsLayer I neuronsPrimate cerebral cortexCajal-Retzius cellsSubpial granular layerGABAergic neuronsGABAergic interneuronsCortical plateI neuronsGanglionic eminenceMacaque monkeysPial surfaceOlfactory primordiumI cellsNeuronsMonth periodLong gestationGranular layerCortexUltrastructural analysisCorticogenesisCellsPrimates
1995
Genesis of the retinal pigment epithelium in the macaque monkey
Rapaport D, Rakic P, Yasamura D, LaVail M. Genesis of the retinal pigment epithelium in the macaque monkey. The Journal Of Comparative Neurology 1995, 363: 359-376. PMID: 8847405, DOI: 10.1002/cne.903630303.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumCell genesisRPE cellsPeripheral retinaRadiolabelled cellsPigment epitheliumRhesus monkey fetusesCells/Embryonic day 25Time of birthMonkey fetusesCentral retinaPostnatal monthPostnatal periodLabeling indexDay 204Macaque monkeysDay 25RetinaJuvenile retinaOptic cupEpitheliumHigh rateNeuroretinaLast cell
1994
Early neurogenesis in the anterior hypothalamus of the rhesus monkey
van Eerdenburg F, Rakic P. Early neurogenesis in the anterior hypothalamus of the rhesus monkey. Brain Research 1994, 79: 290-296. PMID: 7955328, DOI: 10.1016/0165-3806(94)90134-1.Peer-Reviewed Original ResearchConceptsAnterior hypothalamusRhesus monkeysNeurogenetic gradientsPrimate hypothalamusParaventricular nucleusGestational periodVentral gradientSupraoptic nucleusMonkey neuronsHypothalamusNeuronal generationNeuronsEarly neurogenesisSpecific nucleiNeurogenesisMonkeysEarly stagesSpecific differencesGestationNucleusWeeks
1991
Cytogenesis in the monkey retina
la Vail M, Rapaport D, Rakic P. Cytogenesis in the monkey retina. The Journal Of Comparative Neurology 1991, 309: 86-114. PMID: 1894769, DOI: 10.1002/cne.903090107.Peer-Reviewed Original Research
1990
Neurogenesis of the magnocellular basal forebrain nuclei in the rhesus monkey
Kordower J, Rakic P. Neurogenesis of the magnocellular basal forebrain nuclei in the rhesus monkey. The Journal Of Comparative Neurology 1990, 291: 637-653. PMID: 2329194, DOI: 10.1002/cne.902910410.Peer-Reviewed Original ResearchConceptsBasal forebrain nucleiMagnocellular basal forebrain nucleiBasal forebrainForebrain nucleiRhesus monkeysAnterior basal forebrainEmbryonic day 27Early postnatal periodPeak of neurogenesisCortical-cortical connectionsNucleus basalisNeurogenic gradientCortical neuronsDays gestationMagnocellular neuronsPostnatal periodTarget neuronsNeuronal genesisCortical mantleMagnocellular nucleusPregnant animalsDay 27Intermediate divisionGestationPosterior division
1988
Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey
Eckenhoff M, Rakic P. Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey. Journal Of Neuroscience 1988, 8: 2729-2747. PMID: 3411351, PMCID: PMC6569394, DOI: 10.1523/jneurosci.08-08-02729.1988.Peer-Reviewed Original ResearchConceptsProliferative cellsMitotic divisionPostmitotic cellsUltra-structural characteristicsPossible functionsElectron microscopic levelStable populationGlial fibrillary acidic proteinNeuronal cellsStem cellsJuvenile periodMajor classesMature primatesSubgranular zoneDentate gyrusGlial cellsLife spanCellsGFAP-negative cellsFateRhesus monkeysAcidic proteinNew neuronsPostpubertal animalsFibrillary acidic protein
1985
DNA Synthesis and Cell Division in the Adult Primate Braina
RAKIC P. DNA Synthesis and Cell Division in the Adult Primate Braina. Annals Of The New York Academy Of Sciences 1985, 457: 193-211. PMID: 3913364, DOI: 10.1111/j.1749-6632.1985.tb20806.x.Peer-Reviewed Original ResearchConceptsPostembryonic neurogenesisNonmammalian vertebratesCell divisionDNA precursorsPrimate central nervous systemStable populationDNA synthesisNonprimate mammalsCentral nervous systemMature primatesNeuronal additionGlial cellsNervous systemAdult monkeysRetention of memoryAutoradiographic analysisMultiple injectionsVertebratesDevelopmental periodMammalsVariable degreesNeuronsJuvenilesNeurogenesisTurnover
1981
The total number, time of origin and kinetics of proliferation of neurons comprising the deep cerebellar nuclei in the rhesus monkey
Gould B, Rakic P. The total number, time of origin and kinetics of proliferation of neurons comprising the deep cerebellar nuclei in the rhesus monkey. Experimental Brain Research 1981, 44: 195-206. PMID: 7286107, DOI: 10.1007/bf00237341.Peer-Reviewed Original ResearchConceptsCerebellar nucleiPosterior interposed nucleusDeep nucleiSmall neuronsDentate nucleusFastigial nucleusRhesus monkeysInterposed nucleusCessation of neurogenesisGenesis of neuronsPostnatal rhesus monkeysIntermediate time courseDay gestation periodDeep cerebellar nucleiPostnatal ageCerebellar cortexAxonal connectionsOld monkeysNeuron populationsKinetics of proliferationNeuronsAutoradiographic methodTotal numberNeurogenesisPeak of proliferation
1980
Neurogenesis of the nucleus accumbens septi and neighboring septal nuclei in the rhesus monkey: A combined [3H]thymidine and electron microscopic study
Brand S, Rakic P. Neurogenesis of the nucleus accumbens septi and neighboring septal nuclei in the rhesus monkey: A combined [3H]thymidine and electron microscopic study. Neuroscience 1980, 5: 2125-2138. PMID: 7465048, DOI: 10.1016/0306-4522(80)90128-1.Peer-Reviewed Original ResearchConceptsNucleus accumbens septiMedial septal nucleusSeptal nucleusAccumbens septiRhesus monkeysEmbryonic day 45Lateral septal nucleusEarly postnatal daysPattern of neurogenesisCommon embryological originDifferent embryonic daysPostnatal dayNeuronal productionNucleus accumbensNeuron distributionDay 85SeptiPrimate neostriatumPial surfaceOld monkeysDay 45NeuronsElectron microscopic studyEmbryological originAutoradiographic analysis
1979
Genesis of the primate neostriatum: [3H]thymidine autoradiographic analysis of the time of neuron origin in the rhesus monkey
Brand S, Rakic P. Genesis of the primate neostriatum: [3H]thymidine autoradiographic analysis of the time of neuron origin in the rhesus monkey. Neuroscience 1979, 4: 767-778. PMID: 113693, DOI: 10.1016/0306-4522(79)90005-8.Peer-Reviewed Original ResearchConceptsNeuron originSmall neuronsPrimate neostriatumRhesus monkeysEarly postnatal daysClasses of neuronsCell body diameterStriatal neurogenesisLarge cellsPostnatal daySingle coronal sectionsNeuronal distributionCaudate nucleusNeuronal proliferationCoronal sectionsDay 43Autoradiographic studyNeostriatumDay 36NeuronsAutoradiographic analysisMonkeysMaximum diameterPutamenDays
1977
Prenatal development of the visual system in rhesus monkey
Rakic P, Barlow H, Gaze R. Prenatal development of the visual system in rhesus monkey. Philosophical Transactions Of The Royal Society B Biological Sciences 1977, 278: 245-260. PMID: 19781, DOI: 10.1098/rstb.1977.0040.Peer-Reviewed Original ResearchConceptsLateral geniculate bodyRetinal ganglion cellsSuperior colliculusOcular dominance columnsLayer IVFirst retinal ganglion cellsRhesus monkeysDorsal lateral geniculate bodySegregation of afferentsPrenatal developmentAnterograde axoplasmic transportEarly postnatal daysProduction of neuronsPrimary visual cortexJuvenile rhesus monkeysSC projectionsEye injectionTransneuronal transportGeniculate bodyCortical plateGanglion cellsGeniculocortical axonsOptic radiationPostnatal dayOcular dominance
1974
CLEARANCE RATE OF EXOGENOUS 3H‐THYMIDINE FROM THE PLASMA OF PREGNANT RHESUS MONKEYS
Nowakowski R, Rakic P. CLEARANCE RATE OF EXOGENOUS 3H‐THYMIDINE FROM THE PLASMA OF PREGNANT RHESUS MONKEYS. Cell Proliferation 1974, 7: 189-194. PMID: 4205927, DOI: 10.1111/j.1365-2184.1974.tb00411.x.Peer-Reviewed Original ResearchNeurons in Rhesus Monkey Visual Cortex: Systematic Relation between Time of Origin and Eventual Disposition
Rakic P. Neurons in Rhesus Monkey Visual Cortex: Systematic Relation between Time of Origin and Eventual Disposition. Science 1974, 183: 425-427. PMID: 4203022, DOI: 10.1126/science.183.4123.425.Peer-Reviewed Original Research
1973
Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neurons
Rakic P. Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neurons. The Journal Of Comparative Neurology 1973, 147: 523-546. PMID: 4122708, DOI: 10.1002/cne.901470407.Peer-Reviewed Original ResearchWeaver Mutant Mouse Cerebellum: Defective Neuronal Migration Secondary to Abnormality of Bergmann Glia
Rakic P, Sidman R. Weaver Mutant Mouse Cerebellum: Defective Neuronal Migration Secondary to Abnormality of Bergmann Glia. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 240-244. PMID: 4509657, PMCID: PMC433223, DOI: 10.1073/pnas.70.1.240.Peer-Reviewed Original ResearchConceptsDefective neuronal migrationGene dosage effectPrimary cellular targetSite of genesisGenetic lociCellular targetsPrimary genetic abnormalityCell deathBergmann glial cellsDosage effectCellular levelGranule cell deathNeuronal migrationCell processesCell genesisNeurological mutantPhenotypic expressionBergmann glial processesGlial cellsCell neuronsGenetic abnormalitiesYoung neuronsWv/wvCerebellum of miceGlial abnormalities
1969
Telencephalic origin of pulvinar neurons in the fetal human brain
Rakić P, Sidman R. Telencephalic origin of pulvinar neurons in the fetal human brain. Brain Structure And Function 1969, 129: 53-82. PMID: 4186810, DOI: 10.1007/bf00521955.Peer-Reviewed Original ResearchConceptsPulvinar neuronsWeeks of gestationPrevious autoradiographic studiesEnd of gestationRapid Golgi methodFetal human brainSerial horizontal sectionsNumerous proliferating cellsCorpus striatumYoung neuronsLateral ventricleHuman thalamusTelencephalic originThird ventricleNeuron productionSulcus terminalisBipolar cellsGanglionic eminenceAutoradiographic studyPulvinarImmature cellsGolgi methodGestationBrain fragmentsNeurons
1968
Supravital DNA synthesis in the developing human and mouse brain.
RAKIC P, SIDMAN R. Supravital DNA synthesis in the developing human and mouse brain. Journal Of Neuropathology & Experimental Neurology 1968, 27: 246-76. PMID: 5646196, DOI: 10.1097/00005072-196804000-00006.Peer-Reviewed Original ResearchSubcommissural organ and adjacent ependyma: Autoradiographic study of their origin in the mouse brain
Rakic P, Sidman R. Subcommissural organ and adjacent ependyma: Autoradiographic study of their origin in the mouse brain. Developmental Dynamics 1968, 122: 317-335. PMID: 5659133, DOI: 10.1002/aja.1001220210.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyDNA ReplicationEpendymaFemaleMaleMesencephalonMethodsMiceThymidineTritium