2010
Gap Junctions/Hemichannels Modulate Interkinetic Nuclear Migration in the Forebrain Precursors
Liu X, Hashimoto-Torii K, Torii M, Ding C, Rakic P. Gap Junctions/Hemichannels Modulate Interkinetic Nuclear Migration in the Forebrain Precursors. Journal Of Neuroscience 2010, 30: 4197-4209. PMID: 20335455, PMCID: PMC2861434, DOI: 10.1523/jneurosci.4187-09.2010.Peer-Reviewed Original Research4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAdenosine TriphosphateAnimalsBoron CompoundsBromodeoxyuridineCalciumCalcium SignalingCarbenoxoloneCell Line, TumorCell MovementCell NucleusCerebral VentriclesChelating AgentsConnexin 43Cyclooxygenase InhibitorsEgtazic AcidEmbryo, MammalianFemaleGap JunctionsGreen Fluorescent ProteinsKi-67 AntigenMeclofenamic AcidMiceNeuroblastomaNeuronsOrgan Culture TechniquesPatch-Clamp TechniquesPlatelet Aggregation InhibitorsPregnancyProsencephalonPyridoxal PhosphateStem Cells
2000
Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain
Laywell E, Rakic P, Kukekov V, Holland E, Steindler D. Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 13883-13888. PMID: 11095732, PMCID: PMC17670, DOI: 10.1073/pnas.250471697.Peer-Reviewed Original ResearchConceptsCentral nervous systemNeural stem cellsAstrocyte monolayersMultipotent astrocytic stem cellsAstrocytic stem cellsPostnatal central nervous systemAdult mouse brainStem cellsCerebral cortexPostnatal wkSpinal cordAdult brainSubependymal zoneNervous systemEpendymal cellsMouse brainMammalian brainSpherical clonesCNS developmentBrainVivo identificationAstrocytesMature forebrainCritical periodCE cellsDifferential Modulation of Proliferation in the Neocortical Ventricular and Subventricular Zones
Haydar T, Wang F, Schwartz M, Rakic P. Differential Modulation of Proliferation in the Neocortical Ventricular and Subventricular Zones. Journal Of Neuroscience 2000, 20: 5764-5774. PMID: 10908617, PMCID: PMC3823557, DOI: 10.1523/jneurosci.20-15-05764.2000.Peer-Reviewed Original ResearchMeSH Keywords6-Cyano-7-nitroquinoxaline-2,3-dioneAnimalsAntimetabolitesBromodeoxyuridineCell DifferentiationCell DivisionCell MovementCerebral VentriclesClone CellsExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsFetusGABA AgonistsGABA AntagonistsGamma-Aminobutyric AcidGlutamic AcidKainic AcidMiceMice, Inbred ICRMuscimolNeocortexNeuronsOrgan Culture TechniquesStem CellsConceptsVentricular zoneNeural progenitor populationsNeural progenitor proliferationSubventricular zoneProgenitor populationsCell cycleProgenitor cloneProgenitor proliferationEmbryonic cerebrumNeocortical growthProliferationDifferential responsivenessRecent studiesBromodeoxyuridine uptakeDifferential modulationOrganotypic slice culturesClassical neurotransmitters GABAOpposite effectNeurotransmitter GABARelative contributionClonesDisparate effectsRegulationSlice culturesSpecific GABA
1998
Young neurons for old brains?
Rakic P. Young neurons for old brains? Nature Neuroscience 1998, 1: 645-647. PMID: 10196576, DOI: 10.1038/3643.Peer-Reviewed Original Research
1997
Restrictive clonal allocation in the chimeric mouse brain
Kuan C, Elliott E, Flavell R, Rakic P. Restrictive clonal allocation in the chimeric mouse brain. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 3374-3379. PMID: 9096401, PMCID: PMC20377, DOI: 10.1073/pnas.94.7.3374.Peer-Reviewed Original ResearchConceptsBrain regionsChimeric mouse brainsMammalian cerebral cortexDifferent brain regionsCerebral cortexCerebral neocortexChimeric miceMouse brainChimeric brainsMammalian brainProgenitor cellsBrainClones of cellsNeocortexStem cellsBlastocyst embryosCellsDifferent subsetsVast majorityCell descendantsPrevious studiesCortexMice
1995
Radial and horizontal deployment of clonally related cells in the primate neocortex: Relationship to distinct mitotic lineages
Kornack D, Rakic P. Radial and horizontal deployment of clonally related cells in the primate neocortex: Relationship to distinct mitotic lineages. Neuron 1995, 15: 311-321. PMID: 7646888, DOI: 10.1016/0896-6273(95)90036-5.Peer-Reviewed Original Research
1991
Glial cell lineage in the cerebral cortex: A review and synthesis
Cameron R, Rakic P. Glial cell lineage in the cerebral cortex: A review and synthesis. Glia 1991, 4: 124-137. PMID: 1827774, DOI: 10.1002/glia.440040204.Peer-Reviewed Original ResearchConceptsCerebral cortexCell lineagesCell lineage relationshipsGlial cellsCortical gliogenesisCell-cell interactionsProgenitor cell poolGlial cell lineagesCentral nervous systemLineage relationshipsNervous systemCell poolLineagesGliogenesisCortexPresent reviewFunctional levelCellsPrecise timingDiversityReviewSeries of stepsCerebrum
1990
Principles of neural cell migration
Rakic P. Principles of neural cell migration. Cellular And Molecular Life Sciences 1990, 46: 882-891. PMID: 2209797, DOI: 10.1007/bf01939380.Peer-Reviewed Original ResearchConceptsNervous systemMammalian central nervous systemClasses of neuronsCentral nervous systemNeural cell migrationAdult nervous systemCell migrationNeuronal cell migrationImmature neuronsBrain abnormalitiesSynaptic connectivityFinal mitotic divisionMolecular cuesNeuronsDistant structuresProliferative centersNeuron positionCell-cell interactionsCell morphologyCongenitalAbnormalitiesBrain