Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian
Qi H, Rand M, Wu X, Sestan N, Wang W, Rakic P, Xu T, Artavanis-Tsakonas S. Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian. Science 1999, 283: 91-94. PMID: 9872749, DOI: 10.1126/science.283.5398.91.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsCell LineCells, CulturedDisintegrinsDrosophilaDrosophila ProteinsFemaleIntracellular Signaling Peptides and ProteinsLigandsMaleMembrane ProteinsMetalloendopeptidasesMolecular Sequence DataMutationNeuronsProtein Processing, Post-TranslationalReceptors, NotchSignal TransductionTransfectionConceptsLigand DeltaMetalloprotease KuzbanianCell fate determinationNotch ligand DeltaFate determinationNotch proteinsTransmembrane ligandsNotch activityProcessing eventsExtracellular fragmentGenetic analysisNotch ligandsSurface receptorsKuzbanianAdjacent cellsSoluble formBroad spectrumNotchSignalingProteinLigandsCellsFragmentsVivoReceptors