2009
Decision by division: making cortical maps
Rakic P, Ayoub AE, Breunig JJ, Dominguez MH. Decision by division: making cortical maps. Trends In Neurosciences 2009, 32: 291-301. PMID: 19380167, PMCID: PMC3601545, DOI: 10.1016/j.tins.2009.01.007.Peer-Reviewed Original ResearchConceptsNeuronal fate determinationFate determinationFinal mitotic divisionEvolutionary expansionCell determinationMitotic divisionProtomap hypothesisEarly specificationLatest compendiumBiological basisProliferative zoneNeuronal classesNewborn neuronsBroad spectrumDivisionGenesHuman neocortexCortical malformationsNeuronsRadial unitsCompendiumMigrationCerebral wall
2001
Cell Proliferation Without Neurogenesis in Adult Primate Neocortex
Kornack D, Rakic P. Cell Proliferation Without Neurogenesis in Adult Primate Neocortex. Science 2001, 294: 2127-2130. PMID: 11739948, DOI: 10.1126/science.1065467.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAstrocytesBrainBromodeoxyuridineCell DeathCell DivisionCell MovementEndothelium, VascularFemaleFluorescent Antibody TechniqueGlial Fibrillary Acidic ProteinImmunoenzyme TechniquesMacaca fascicularisMacaca mulattaMaleMicroscopy, ConfocalMicroscopy, FluorescenceNeocortexNeuronsNuclear ProteinsTubulinConceptsPrimate neocortexGlial cell markersAdult macaque monkeysNew neuronsNumerous BrdUOlfactory bulbCerebral wallAdult macaquesMacaque monkeysNonneuronal cellsHigher cognitive functionsCell markersCognitive functionNeocortexNeurogenesisTriple labelingCellular mechanismsCell proliferationNeuronsCellsHippocampus
1996
Role of neuron-glial junctional domain proteins in the maintenance and termination of neuronal migration across the embryonic cerebral wall
Anton E, Cameron R, Rakic P. Role of neuron-glial junctional domain proteins in the maintenance and termination of neuronal migration across the embryonic cerebral wall. Journal Of Neuroscience 1996, 16: 2283-2293. PMID: 8601808, PMCID: PMC6578523, DOI: 10.1523/jneurosci.16-07-02283.1996.Peer-Reviewed Original ResearchConceptsEmbryonic cerebral wallCerebral wallNeuronal migrationCerebral cortexNeuronal migratory pathwayRadial glial cell processesRadial glial fibersGlial cell processesNormal neuronal migrationCortical plateSlice preparationAntibody exposureGlial fibersMarginal zone regionsMonoclonal antibodiesAntibodiesNeuronsCortexCell substratesMarginal zonePolyclonal antiserumMicrotubular organizationCell processesMigratory pathwaysCell detachment
1995
Neurotransmitter receptors in the proliferative zones of the developing primate occipital lobe
Lidow M, Rakic P. Neurotransmitter receptors in the proliferative zones of the developing primate occipital lobe. The Journal Of Comparative Neurology 1995, 360: 393-402. PMID: 8543647, DOI: 10.1002/cne.903600303.Peer-Reviewed Original ResearchConceptsCortical neuronsOccipital lobeReceptor subtypesSubventricular zoneHigh-affinity kainate receptorsProliferative zoneSubventricular proliferative zonesNeurotransmitter receptor subtypesCell proliferationEmbryonic cerebral wallGamma-aminobutyric acidD1 dopaminergicMonkey fetusesDeep laminaeKainate receptorsNeuronal productionCerebral wallMultiple neurotransmittersCortical neurogenesisNeurotransmitter receptorsVisual cortexFetusesNeuronsAlpha 1Alpha 2
1994
Unique profiles of the alpha 1-, alpha 2-, and beta-adrenergic receptors in the developing cortical plate and transient embryonic zones of the rhesus monkey
Lidow, Rakic P. Unique profiles of the alpha 1-, alpha 2-, and beta-adrenergic receptors in the developing cortical plate and transient embryonic zones of the rhesus monkey. Journal Of Neuroscience 1994, 14: 4064-4078. PMID: 8027763, PMCID: PMC6577033, DOI: 10.1523/jneurosci.14-07-04064.1994.Peer-Reviewed Original ResearchConceptsTransient embryonic zonesBeta-adrenergic receptorsCortical plateAdrenergic receptor subtypesSubplate zoneReceptor subtypesCerebral wallRhesus monkeysAlpha 1Alpha 1 sitesAlpha 2Alpha 2 receptorsAlpha 1 receptorsEmbryonic zonesIntensive proliferative activityReceptor autoradiographyCortical neuronsSubventricular zoneCortical developmentOccipital lobeBeta receptorsAdrenergic receptorsAdrenergic sitesVisual cortexGerminal zone
1990
Developmental history of the transient subplate zone in the visual and somatosensory cortex of the macaque monkey and human brain
Kostovic I, Rakic P. Developmental history of the transient subplate zone in the visual and somatosensory cortex of the macaque monkey and human brain. The Journal Of Comparative Neurology 1990, 297: 441-470. PMID: 2398142, DOI: 10.1002/cne.902970309.Peer-Reviewed Original ResearchConceptsSubplate zoneTransient subplate zoneCortical plateSomatosensory cortexSubcortical white matterSubplate neuronsBasal forebrainBrain stemContralateral cerebralGlial cellsPostmigratory neuronsSomatosensory areaFetal brainOccipital lobeCerebral convolutionsCerebral wallFiber terminalsHuman fetusesWhite matterMacaque monkeysVisual areasCortexGestationFiber-rich layersHistochemical methods
1979
A golgi study of radial glial cells in developing monkey telencephalon: Morphogenesis and transformation into astrocytes
Schmechel D, Rakic P. A golgi study of radial glial cells in developing monkey telencephalon: Morphogenesis and transformation into astrocytes. Brain Structure And Function 1979, 156: 115-152. PMID: 111580, DOI: 10.1007/bf00300010.Peer-Reviewed Original ResearchConceptsRadial glial cellsGlial cellsCerebral wallSubventricular zoneOccipital lobeRadial fibersPial surfaceRadial glial fibersRapid Golgi methodMedial cerebral wallMonkey telencephalonCalcarine fissureCortical plateGolgi studyLateral ventricleProtoplasmic astrocytesLarge oval nucleiDay 365Ependymal cellsGlial fibersAstrocytesRhesus monkeysOlder ageDay 48Oval nuclei