2022
Preparatory neurons for building a nest
Iyilikci O, Dietrich MO. Preparatory neurons for building a nest. Neuron 2022, 110: 1283-1285. PMID: 35447098, DOI: 10.1016/j.neuron.2022.03.023.Peer-Reviewed Original ResearchDevelopment of “Hunger Neurons” and the Unanticipated Relationship Between Energy Metabolism and Mother-Infant Interactions
Iyilikci O, Zimmer MR, Dietrich MO. Development of “Hunger Neurons” and the Unanticipated Relationship Between Energy Metabolism and Mother-Infant Interactions. Biological Psychiatry 2022, 91: 907-914. PMID: 35397878, PMCID: PMC10184517, DOI: 10.1016/j.biopsych.2022.02.962.Peer-Reviewed Original Research
2020
AgRP neurons control compulsive exercise and survival in an activity-based anorexia model
Miletta MC, Iyilikci O, Shanabrough M, Šestan-Peša M, Cammisa A, Zeiss CJ, Dietrich MO, Horvath TL. AgRP neurons control compulsive exercise and survival in an activity-based anorexia model. Nature Metabolism 2020, 2: 1204-1211. PMID: 33106687, DOI: 10.1038/s42255-020-00300-8.Peer-Reviewed Original ResearchConceptsAgRP neuronsActivity-based anorexia modelAgRP neuronal activityVivo fiber photometryFood-restricted miceFood-restricted animalsCompulsive exerciseAnorexia modelHypothalamic agoutiNeuropeptide YExercise volumeFood intakeMouse modelNeuronal activityFiber photometryDaily activationNeuronal circuitsPsychiatric conditionsAnorexia nervosaChemogenetic toolsNeuronsLong-term behavioral impactElevated fat contentVoluntary cessationFat content
2019
Functional Ontogeny of Hypothalamic Agrp Neurons in Neonatal Mouse Behaviors
Zimmer MR, Fonseca AHO, Iyilikci O, Pra RD, Dietrich MO. Functional Ontogeny of Hypothalamic Agrp Neurons in Neonatal Mouse Behaviors. Cell 2019, 178: 44-59.e7. PMID: 31104844, PMCID: PMC6688755, DOI: 10.1016/j.cell.2019.04.026.Peer-Reviewed Original ResearchConceptsHypothalamic AgRP neuronsAgRP neuronsAdult micePostnatal day 10 miceVivo fiber photometryFunctional ontogenyIsolation-induced ultrasonic vocalizationsNon-nutritive sucklingUltrasonic vocalizationsMilk ingestionFiber photometryMilk deprivationFood ingestionNeuronsMiceMouse behaviorIngestionNeonatesGABALittermatesOveractivation
2014
Fos Expression in Monoaminergic Cell Groups in Response to Sociosexual Interactions in Male and Female Japanese Quail
Iyilikci O, Baxter S, Balthazart J, Ball G. Fos Expression in Monoaminergic Cell Groups in Response to Sociosexual Interactions in Male and Female Japanese Quail. Behavioral Neuroscience 2014, 128: 48-60. PMID: 24512065, PMCID: PMC3963440, DOI: 10.1037/a0035427.Peer-Reviewed Original ResearchConceptsRhythmic cloacal sphincter movementsMonoaminergic cell groupsAppetitive sexual behaviorFos expressionCell groupsTyrosine hydroxylaseSexual behaviorTryptophan hydroxylaseFos-immunoreactive cellsDouble-label immunohistochemistryVentral tegmental areaDopaminergic cell groupsMedial preoptic nucleusRaphe pallidusSerotoninergic systemFemale Japanese quailTegmental areaMonoaminergic neurotransmittersDopaminergic systemPreoptic nucleusStria terminalisBed nucleusDifferent cell groupsFos inductionIndolaminergic cells
2009
Blue but not red light stimulation in the dark has antidepressant effect in behavioral despair
İyilikci O, Aydin E, Canbeyli R. Blue but not red light stimulation in the dark has antidepressant effect in behavioral despair. Behavioural Brain Research 2009, 203: 65-68. PMID: 19379775, DOI: 10.1016/j.bbr.2009.04.013.Peer-Reviewed Original ResearchConceptsAntidepressant effectsSwim testSecond swim testBehavioral despairMelanopsin-containing ganglion cellsPotential antidepressant effectsMale Wistar ratsDuration of immobilityLight stimulationGanglion cellsWistar ratsPulse administrationControl groupPhotic stimulationDark onsetPhotic exposureRed light stimulationStimulationPresent findingsDark phaseBlue light stimulationPresent studyExposureImmobilityLight exposure