2024
Global Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database.
Alhajahjeh A, Rotter L, Stempel J, Grimshaw A, Bewersdorf J, Blaha O, Kewan T, Podoltsev N, Shallis R, Mendez L, Stahl M, Zeidan A. Global Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database. JCO Global Oncology 2024, 10: e2400316. PMID: 39621951, DOI: 10.1200/go-24-00316.Peer-Reviewed Original ResearchAnalyzing determinants of premature trial discontinuation in leukemia clinical trials
Rotter L, Alhajahjeh A, Stempel J, Grimshaw A, Bewersdorf J, Blaha O, Kewan T, Podoltsev N, Shallis R, Mendez L, Stahl M, Zeidan A. Analyzing determinants of premature trial discontinuation in leukemia clinical trials. Leukemia & Lymphoma 2024, ahead-of-print: 1-9. PMID: 39440622, DOI: 10.1080/10428194.2024.2416565.Peer-Reviewed Original ResearchClinical trialsSlow accrualLeukemia trialsEarly-phase trialsNon-randomized trialsAcademic-sponsored trialsImprove patient outcomesLeukemia clinical trialsSingle-centerTrial discontinuationSponsored trialsSmall trialsLeukemiaEarly terminationPatient outcomesLate-phaseIndependent reviewersTermination ratesComprehensive searchTrials
2023
Taking a chance: How likely am I to receive my preferred treatment in a clinical trial?
Walter S, Blaha O, Esserman D. Taking a chance: How likely am I to receive my preferred treatment in a clinical trial? Statistical Methods In Medical Research 2023, 32: 572-592. PMID: 36628522, PMCID: PMC9983058, DOI: 10.1177/09622802221146305.Peer-Reviewed Original ResearchConceptsPatient preference designConcordance ratePreferred treatmentClinical trialsDifferent treatment preferencesProportion of patientsParallel group designPreference designPatient's primary motivationTrial patientsPoor outcomeBlinded trialClinical equipoiseTreatment preferencesTwo-armZelen designAlternative treatmentStudy outcomesStudy designTrialsTreatmentPatientsPotential participantsOutcomesGroup design