2017
Outcomes Related to the Use of Frozen Plasma or Pooled Solvent/Detergent-Treated Plasma in Critically Ill Children*
Camazine MN, Karam O, Colvin R, Leteurtre S, Demaret P, Tucci M, Muszynski JA, Stanworth S, Spinella PC. Outcomes Related to the Use of Frozen Plasma or Pooled Solvent/Detergent-Treated Plasma in Critically Ill Children*. Pediatric Critical Care Medicine 2017, 18: e215-e223. PMID: 28350560, DOI: 10.1097/pcc.0000000000001149.Peer-Reviewed Original ResearchConceptsSolvent detergent plasmaPlasma 24 hoursICU mortalityIll childrenPlasma transfusionStudy groupHours groupPretransfusion international normalized ratioSolvent/detergent-treated plasmaCritically Ill ChildrenInternational normalized ratioHypothesis-generating dataMultivariable logistic regressionIllness scoresImproved survivalMedian ageAdjusted analysisNormalized ratioPrimary indicationIndependent associationFrozen plasmaObservational studyPlasma useLactate valuesPatients
2010
Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients
Gauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, Hébert PC, Hutchison JS, Hume HA, Tucci M, Network O. Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion 2010, 50: 1902-1913. PMID: 20456697, DOI: 10.1111/j.1537-2995.2010.02661.x.Peer-Reviewed Original ResearchConceptsMultiple organ dysfunction syndromeProgressive multiple organ dysfunction syndromeOrgan dysfunction syndromeIll childrenDysfunction syndromePediatric Logistic Organ Dysfunction scoreRed blood cell storage timeLogistic Organ Dysfunction scorePediatric intensive care patientsOrgan dysfunction scoreIntensive care patientsRBC storage timeMultivariate logistic regressionRed blood cellsDysfunction scoreCare patientsRestrictive groupIndependent associationCohort analysisPatientsHigh mortalityGreater riskLogistic regressionRBC unitsStudy design