2012
Effects on post-prandial glucose and AGE precursors from two initial insulin strategies in patients with Type 2 diabetes uncontrolled by oral agents
Sakharova OV, Lleva RR, Dziura JD, Spollett GR, Howell SK, Beisswenger PJ, Inzucchi SE. Effects on post-prandial glucose and AGE precursors from two initial insulin strategies in patients with Type 2 diabetes uncontrolled by oral agents. Journal Of Diabetes And Its Complications 2012, 26: 333-338. PMID: 22541894, DOI: 10.1016/j.jdiacomp.2012.03.027.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAgedBlood GlucoseBody WeightCross-Over StudiesDiabetes Mellitus, Type 2FastingFemaleGlycated HemoglobinGlycation End Products, AdvancedHumansHypoglycemic AgentsInsulin GlargineInsulin LisproInsulin, Long-ActingMaleMiddle AgedPostprandial PeriodTreatment FailureTreatment OutcomeConceptsOral anti-hyperglycemic drugsPost-prandial glucoseInsulin strategiesFree fatty acidsType 2Post-prandial glucose metabolismProgressive β-cell dysfunctionType 2 diabetes patientsPost-prandial glucose levelsDaily insulin glargineInitial insulin regimenPrecursor of AGEsSingle-center studyClinical Research CenterLong-term diabetic complicationsAnti-hyperglycemic drugsType 2 diabetesΒ-cell dysfunctionCross-over designInitial insulinInsulin regimenOral agentsInsulin regimensInsulin therapyOAD therapy
2008
Cyclic Rapid Fluctuation of Hypertension and Hypotension in Pheochromocytoma
Ionescu CN, Sakharova OV, Harwood MD, Caracciolo EA, Schoenfeld MH, Donohue TJ. Cyclic Rapid Fluctuation of Hypertension and Hypotension in Pheochromocytoma. Journal Of Clinical Hypertension 2008, 10: 936-940. PMID: 19120720, PMCID: PMC8673043, DOI: 10.1111/j.1751-7176.2008.00046.x.Peer-Reviewed Original Research
2007
Endocrine Assessments During Critical Illness
Sakharova OV, Inzucchi SE. Endocrine Assessments During Critical Illness. Critical Care Clinics 2007, 23: 467-490. PMID: 17900481, DOI: 10.1016/j.ccc.2007.05.007.Peer-Reviewed Original Research
2006
"Glucometrics"--assessing the quality of inpatient glucose management.
Goldberg PA, Bozzo JE, Thomas PG, Mesmer MM, Sakharova OV, Radford MJ, Inzucchi SE. "Glucometrics"--assessing the quality of inpatient glucose management. Diabetes Technology & Therapeutics 2006, 8: 560-9. PMID: 17037970, DOI: 10.1089/dia.2006.8.560.Peer-Reviewed Original ResearchConceptsInpatient glycemic controlGlycemic controlBG levelsGlucose managementGlucose levelsVenous plasma glucose levelsOutpatient glycemic controlStrict glycemic controlGeneral hospital wardsGold standardPlasma glucose levelsVenous glucose levelsBlood glucose managementInpatient glucose managementPatient care unitsQuality improvement initiativesIntensive care unit dataMedian BG levelHospitalized patientsCare unitIll patientsBlood samplesHospital wardsEvent ratesPatients
2005
Treatment of diabetes in the elderly
Sakharova OV, Inzucchi SE. Treatment of diabetes in the elderly. Postgraduate Medicine 2005, 118: 19-29. PMID: 16329527, DOI: 10.3810/pgm.2005.11.1684.Peer-Reviewed Original ResearchConceptsMajor public health concernType 2 diabetesOverview of therapiesHost of comorbiditiesTreatment of diabetesPublic health concernEvidence-based informationAntidiabetic agentsTherapeutic goalsDiabetes treatmentDiabetesOlder populationHealth concernOlder adultsPrevalent formTreatmentMedical picturesComorbiditiesTherapy
2004
Improving glycemic control in the cardiothoracic intensive care unit: Clinical experience in two hospital settings
Goldberg PA, Sakharova OV, Barrett PW, Falko LN, Roussel MG, Bak L, Blake-Holmes D, Marieb NJ, Inzucchi SE. Improving glycemic control in the cardiothoracic intensive care unit: Clinical experience in two hospital settings. Journal Of Cardiothoracic And Vascular Anesthesia 2004, 18: 690-697. PMID: 15650975, DOI: 10.1053/j.jvca.2004.08.003.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood GlucoseCardiac Surgical ProceduresCohort StudiesDrug MonitoringFemaleHospitals, CommunityHospitals, TeachingHumansHyperglycemiaHypoglycemic AgentsInfusions, IntravenousInsulinInsulin Infusion SystemsIntensive Care UnitsMalePostoperative ComplicationsProspective StudiesTime FactorsTreatment OutcomeConceptsIntensive insulin infusion protocolCardiothoracic intensive care unitIntensive care unitGlycemic controlBG levelsCare unitBG valuesCTICU patientsPerioperative glycemic controlRelevant baseline variablesTarget BG levelProspective cohort studyStrict glycemic controlTertiary referral hospitalAdverse clinical eventsInsulin infusion protocolCommunity teaching hospitalBlood glucose levelsNarrow target rangeCohort studyHospital chartsReferral hospitalClinical outcomesMedian timeClinical events
2001
Vasopeptidase inhibition affords greater renoprotection than angiotensin-converting enzyme inhibition alone.
Taal MW, Nenov VD, Wong W, Satyal SR, Sakharova O, Choi JH, Troy JL, Brenner BM. Vasopeptidase inhibition affords greater renoprotection than angiotensin-converting enzyme inhibition alone. Journal Of The American Society Of Nephrology : JASN 2001, 12: 2051-2059. PMID: 11562403, DOI: 10.1681/ASN.V12102051.Peer-Reviewed Original Research