2023
Implementation and evaluation of an electronic health record-integrated app for postpartum monitoring of hypertensive disorders of pregnancy using patient-contributed data collection
Dullabh P, Heaney-Huls K, Chiao A, Callaham M, Desai P, Gauthreaux N, Kashyap N, Lobach D, Boxwala A. Implementation and evaluation of an electronic health record-integrated app for postpartum monitoring of hypertensive disorders of pregnancy using patient-contributed data collection. JAMIA Open 2023, 6: ooad098. PMID: 38028731, PMCID: PMC10646567, DOI: 10.1093/jamiaopen/ooad098.Peer-Reviewed Original ResearchElectronic health recordsHypertensive disordersRemote patient monitoring programPostpartum monitoringLocal clinical championsClinical championsPatient involvementIntegration standardsKey observationPilot interventionEHR developersClinician usersHealth recordsClinical workflowRemote monitoringDisordersPregnancyAppsSmartphone applicationInterventionData collectionPatientsDevelopersUsersUsability
2022
Where Do Real-Time Prescription Benefit Tools Fit in the Landscape of High US Prescription Medication Costs? A Narrative Review
Wong R, Mehta T, Very B, Luo J, Feterik K, Crotty B, Epstein J, Fliotsos M, Kashyap N, Smith E, Woreta F, Schwartz J. Where Do Real-Time Prescription Benefit Tools Fit in the Landscape of High US Prescription Medication Costs? A Narrative Review. Journal Of General Internal Medicine 2022, 38: 1038-1045. PMID: 36441366, PMCID: PMC10039141, DOI: 10.1007/s11606-022-07945-z.Peer-Reviewed Original ResearchConceptsMedication costsElectronic clinical decision support toolPocket medication costsPrescription medication costsPoor patient adherenceWorse clinical outcomesClinical decision support toolUS healthcare costsPocket cost informationElectronic health recordsPharmacologic treatmentClinical outcomesPatient adherencePrescription medicationsHealthcare costsPatientsNarrative reviewHealth systemMedicaid ServicesLimited evidenceHealth recordsHealthcare systemFinancial burdenAdherenceMultiple factorsIntegrating a Patient Engagement App into an Electronic Health Record-Enabled Workflow Using Interoperability Standards
Lobach D, Boxwala A, Kashyap N, Heaney-Huls K, Chiao A, Rafter T, Lomotan E, Harrison M, Dymek C, Swiger J, Dullabh P. Integrating a Patient Engagement App into an Electronic Health Record-Enabled Workflow Using Interoperability Standards. Applied Clinical Informatics 2022, 13: 1163-1171. PMID: 36516969, PMCID: PMC9750793, DOI: 10.1055/s-0042-1758736.Peer-Reviewed Original ResearchConceptsFast Healthcare Interoperability ResourcesApplication programming interfaceFHIR standardElectronic health recordsInteroperability standardsApplication development teamClinical workflowCOVID-19 trackerHealth recordsStandards-based approachIntegration of appsFHIR resourcesProgramming interfaceMobile health applicationsMobile applicationsWorkflow integrationDevelopment teamsClinician workflowPartial implementationWorkflowHealth applicationsAppsClinical systemsSuch integrationText messagesAlerting Clinicians to 1-Year Mortality Risk in Patients Hospitalized With Heart Failure
Ahmad T, Desai NR, Yamamoto Y, Biswas A, Ghazi L, Martin M, Simonov M, Dhar R, Hsiao A, Kashyap N, Allen L, Velazquez EJ, Wilson FP. Alerting Clinicians to 1-Year Mortality Risk in Patients Hospitalized With Heart Failure. JAMA Cardiology 2022, 7: 905-912. PMID: 35947362, PMCID: PMC9366654, DOI: 10.1001/jamacardio.2022.2496.Peer-Reviewed Original ResearchConceptsUsual care groupElectronic health recordsHeart failureAlert groupMedian agePrimary outcomeFemale patientsTerminal pro-brain natriuretic peptide levelsYale New Haven Health SystemPro-brain natriuretic peptide levelsMedian NT-proBNP levelLeft ventricular ejection fractionLarge tertiary care centerHeart failure hospitalizationHeart failure medicationsNatriuretic peptide levelsNT-proBNP levelsHealth recordsHours of admissionTertiary care centerVentricular ejection fractionRate of hospitalizationIntensive care unitEthnicity groupsSmall community hospital
2021
Design and rationale of the colchicine/statin for the prevention of COVID-19 complications (COLSTAT) trial
Shah T, McCarthy M, Nasir I, Archer H, Ragheb E, Kluger J, Kashyap N, Paredes C, Patel P, Lu J, Kandel P, Song C, Khan M, Ul Haq F, Ahmad R, Howes C, Cambi B, Lancaster G, Cleman M, Dela Cruz CS, Parise H, Lansky A. Design and rationale of the colchicine/statin for the prevention of COVID-19 complications (COLSTAT) trial. Contemporary Clinical Trials 2021, 110: 106547. PMID: 34461322, PMCID: PMC8397504, DOI: 10.1016/j.cct.2021.106547.Peer-Reviewed Original ResearchConceptsHospitalized COVID-19 patientsCOVID-19 patientsStandard of careElectronic health recordsComplications TrialSevere COVID-19 diseaseWorld Health Organization (WHO) ordinal scaleVenous thromboembolic eventsHealth recordsCombination of colchicineRates of morbidityCOVID-19 diseaseCost-effective treatmentPrimary endpointRespiratory failureThromboembolic eventsClinical improvementMyocardial injuryPragmatic trialClinical trialsPatientsEvent ascertainmentHealth NetworkRosuvastatinTrialsREVeAL-HF Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical Practice
Ahmad T, Yamamoto Y, Biswas A, Ghazi L, Martin M, Simonov M, Hsiao A, Kashyap N, Velazquez EJ, Desai NR, Wilson FP. REVeAL-HF Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical Practice. JACC Heart Failure 2021, 9: 409-419. PMID: 33992566, DOI: 10.1016/j.jchf.2021.03.006.Peer-Reviewed Original ResearchConceptsHeart failurePatient outcomesClinical decision makingN-terminal pro-B-type natriuretic peptide levelsPro-B-type natriuretic peptide levelsPragmatic Randomized Controlled TrialIntravenous diuretic agentsNatriuretic peptide levelsRandomized Controlled TrialsRoutine clinical practiceEvidence-based interventionsElectronic health recordsControlled TrialsPatient populationAccurate prognosticationCommon causeDiuretic agentsPeptide levelsClinical practicePg/TrialsHealth recordsSignificant riskMortalityOutcomes
2018
Analysis of medication therapy discontinuation orders in new electronic prescriptions and opportunities for implementing CancelRx
Yang Y, Ward-Charlerie S, Kashyap N, DeMayo R, Agresta T, Green J. Analysis of medication therapy discontinuation orders in new electronic prescriptions and opportunities for implementing CancelRx. Journal Of The American Medical Informatics Association 2018, 25: 1516-1523. PMID: 30101337, PMCID: PMC6342171, DOI: 10.1093/jamia/ocy100.Peer-Reviewed Original Research
2017
An EPIC electronic decision support tool to identify percentage of patients with stage IV thoracic or gastrointestinal malignancy who would benefit from concurrent palliative care but do not currently receive it.
Adelson K, Trant A, Framski K, Swidler M, Kashyap N. An EPIC electronic decision support tool to identify percentage of patients with stage IV thoracic or gastrointestinal malignancy who would benefit from concurrent palliative care but do not currently receive it. Journal Of Clinical Oncology 2017, 35: 133-133. DOI: 10.1200/jco.2017.35.8_suppl.133.Peer-Reviewed Original ResearchEpic electronic health recordConcurrent palliative carePalliative careOncologic careElectronic decision support toolPalliative care visitsPC referral rateSmilow Cancer HospitalStandard oncologic careYale-New HavenPalliative care consultStage IV diseasePercentage of patientsPalliative care servicesHealth care utilizationICD-10 diagnosisQuality of lifeVolume of patientsElectronic health recordsAlign careCare consultEligible patientsPC referralEnd of lifeIOM guidelines