Trends and Risk Factors for Transfusion in Hepatopancreatobiliary Surgery
Lucas DJ, Schexneider KI, Weiss M, Wolfgang CL, Frank SM, Hirose K, Ahuja N, Makary M, Cameron JL, Pawlik TM. Trends and Risk Factors for Transfusion in Hepatopancreatobiliary Surgery. Journal Of Gastrointestinal Surgery 2013, 18: 719-728. PMID: 24323432, DOI: 10.1007/s11605-013-2417-9.Peer-Reviewed Original ResearchConceptsRisk of transfusionRisk factorsPerioperative transfusionPreoperative hematocritBlood transfusionHPB proceduresPublic Use FilePatient-level risk factorsAnesthesiologists class IVIncidence of transfusionPerioperative blood transfusionPatient-level factorsHigh-risk factorsPatient-specific factorsHepatopancreatobiliary proceduresTransfusion utilizationPreoperative albuminTransfusion rateASA classificationPancreatic resectionHPB surgeryHepatopancreatobiliary surgeryProcedure typeInclusion criteriaTransfusionIncidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases
Karagkounis G, Torbenson MS, Daniel HD, Azad NS, Diaz LA, Donehower RC, Hirose K, Ahuja N, Pawlik TM, Choti MA. Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases. Cancer 2013, 119: 4137-4144. PMID: 24104864, PMCID: PMC3967132, DOI: 10.1002/cncr.28347.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesSurgical therapyBRAF mutationsLiver metastasesKRAS statusPrognostic impactKRAS mutationsMolecular biomarkersThird of patientsRecurrence-free survivalKRAS gene mutationsPrognostic determinantsColorectal metastasesSurgical cohortWorse survivalClinicopathologic factorsIndependent predictorsCancer surgeryClinicopathologic featuresTumor numberPrognostic significanceBRAF analysisColorectal cancerLiver surgeryLower incidence