2020
Association of Treatment Inequity and Ancestry With Pancreatic Ductal Adenocarcinoma Survival
Heller DR, Nicolson NG, Ahuja N, Khan S, Kunstman JW. Association of Treatment Inequity and Ancestry With Pancreatic Ductal Adenocarcinoma Survival. JAMA Surgery 2020, 155: e195047. PMID: 31800002, PMCID: PMC6902102, DOI: 10.1001/jamasurg.2019.5047.Peer-Reviewed Original ResearchConceptsPancreatic ductal adenocarcinomaNational Cancer DatabaseWhite patientsBlack patientsAdvanced diseaseOverall survivalClinical parametersDisease stageCancer DatabaseSurgical proceduresMultivariable Cox proportional hazards regression modelingTreatment inequitiesCox proportional hazards regression modelingPancreatic ductal adenocarcinoma (PDAC) survivalUnadjusted median overall survivalYounger ageProportional hazards regression modelingMedian overall survivalModest survival advantageStage II diseaseNew cancer diagnosesLess chemotherapyResectable cancerCohort studyPrimary outcome
2018
Trends in Outcomes After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy
Gani F, Conca-Cheng AM, Nettles B, Ahuja N, Johnston FM. Trends in Outcomes After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy. Journal Of Surgical Research 2018, 234: 240-248. PMID: 30527480, DOI: 10.1016/j.jss.2018.09.032.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinomaChemotherapy, Cancer, Regional PerfusionCombined Modality TherapyCytoreduction Surgical ProceduresDatabases, FactualFemaleHumansHyperthermia, InducedLogistic ModelsMaleMiddle AgedPatient SelectionPeritoneal NeoplasmsPostoperative ComplicationsRisk FactorsTreatment OutcomeConceptsCRS/HIPECHyperthermic intraperitoneal chemotherapyMedian operative timeLength of stayPostoperative morbidityCytoreductive surgeryOperative timeIntraperitoneal chemotherapySelect patientsClinical outcomesSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseCommon primary tumor siteQuality Improvement Program databaseMultivariable logistic regression analysisLow preoperative hematocritImprovement Program databasePreoperative serum albuminCareful patient selectionPrimary tumor siteLogistic regression analysisPostoperative complicationsPostoperative deathsPreoperative hematocritPeritoneal carcinomatosisComparing the long‐term outcomes among patients with stomach and small intestine gastrointestinal stromal tumors: An analysis of the National Cancer Database
Giuliano K, Ejaz A, Reames BN, Choi W, Sham J, Gage M, Johnston FM, Ahuja N. Comparing the long‐term outcomes among patients with stomach and small intestine gastrointestinal stromal tumors: An analysis of the National Cancer Database. Journal Of Surgical Oncology 2018, 118: 486-492. PMID: 30129672, DOI: 10.1002/jso.25172.Peer-Reviewed Original ResearchConceptsSmall intestine gastrointestinal stromal tumorGastrointestinal stromal tumorsNational Cancer DatabaseOverall survivalStromal tumorsTumor locationCancer DatabaseLarger median tumor sizeStomach gastrointestinal stromal tumorUnadjusted median overall survivalCox proportional hazards modelNational Oncology DatabaseMedian overall survivalMedian tumor sizeWorse prognostic featuresKaplan-Meier methodLong-term prognosisTumor-related factorsLong-term outcomesCases of stomachProportional hazards modelCommon sarcomaTotal patientsPrognostic featuresOncology databaseMinimally Invasive Versus Open Primary Resection for Retroperitoneal Soft Tissue Sarcoma: A Propensity-Matched Study From the National Cancer Database
Gani F, Goel U, Blair AB, Singh J, Overton HN, Meyer CF, Canner JK, Pawlik TM, Ahuja N, Johnston FM. Minimally Invasive Versus Open Primary Resection for Retroperitoneal Soft Tissue Sarcoma: A Propensity-Matched Study From the National Cancer Database. Annals Of Surgical Oncology 2018, 25: 2209-2217. PMID: 29855832, PMCID: PMC8383095, DOI: 10.1245/s10434-018-6538-y.Peer-Reviewed Original ResearchConceptsRetroperitoneal soft tissue sarcomaNational Cancer DatabaseSoft tissue sarcomasUse of MISPostoperative mortalityPrimary resectionOverall survivalClinical outcomesTissue sarcomasCancer DatabaseCox proportional hazards modelShorter hospital lengthProportional hazards modelHospital lengthInvasive VersusMultivariable logisticPelvic cancerShorter LOSOpen surgeryOperative approachCommunity hospitalInclusion criteriaSmall tumorsTreatment groupsHazards model
2016
Understanding the Barriers to Hiring and Promoting Women in Surgical Subspecialties
Valsangkar N, Fecher AM, Rozycki GS, Blanton C, Bell TM, Freischlag J, Ahuja N, Zimmers TA, Koniaris LG. Understanding the Barriers to Hiring and Promoting Women in Surgical Subspecialties. Journal Of The American College Of Surgeons 2016, 223: 387-398.e2. PMID: 27109779, DOI: 10.1016/j.jamcollsurg.2016.03.042.Peer-Reviewed Original ResearchConceptsCardiothoracic surgerySurgical facultyDepartment of SurgeryNIH fundingOverall median numberCertain subspecialtiesSurgical departmentSurgical oncologyMedian numberFraction of womenHigher NIH fundingPublications/citationsObserved lower numberSurgerySurgical subspecialtiesPotential disparitiesWomenDemographic characteristicsFunding detailsSubspecialtyFemale assistant professorsAssistant professor levelDivision chiefsDepartmentMore recent citations
2015
Intraductal papillary mucinous neoplasm (IPMN) with high-grade dysplasia is a risk factor for the subsequent development of pancreatic ductal adenocarcinoma
Rezaee N, Barbon C, Zaki A, He J, Salman B, Hruban RH, Cameron JL, Herman JM, Ahuja N, Lennon AM, Weiss MJ, Wood LD, Wolfgang CL. Intraductal papillary mucinous neoplasm (IPMN) with high-grade dysplasia is a risk factor for the subsequent development of pancreatic ductal adenocarcinoma. Hepato Pancreato Biliary 2015, 18: 236-246. PMID: 27017163, PMCID: PMC4814593, DOI: 10.1016/j.hpb.2015.10.010.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Pancreatic DuctalDatabases, FactualDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLymphatic MetastasisMaleMiddle AgedNeoplasm GradingNeoplasm InvasivenessNeoplasms, Cystic, Mucinous, and SerousNeoplasms, Second PrimaryPancreatectomyPancreatic NeoplasmsProportional Hazards ModelsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsIntraductal papillary mucinous neoplasmHigh-grade dysplasiaPancreatic ductal adenocarcinomaNon-invasive intraductal papillary mucinous neoplasmsIntermediate-grade dysplasiaPapillary mucinous neoplasmRemnant pancreasVascular invasionMucinous neoplasmsDuctal adenocarcinomaInvasive pancreatic ductal adenocarcinomaMedian overall survivalLymph node metastasisRate of progressionSubsequent developmentIntermediate dysplasiaPancreatic resectionOverall survivalNode metastasisPerineural invasionMalignant entitiesRisk factorsPatientsDysplasiaPancreasEarly hospital readmission for gastrointestinal-related complications predicts long-term mortality after pancreatectomy
Hicks CW, Tosoian JJ, Craig-Schapiro R, Valero V, Cameron JL, Eckhauser FE, Hirose K, Makary MA, Pawlik TM, Ahuja N, Weiss MJ, Wolfgang CL. Early hospital readmission for gastrointestinal-related complications predicts long-term mortality after pancreatectomy. The American Journal Of Surgery 2015, 210: 636-642.e1. PMID: 26384793, PMCID: PMC4634566, DOI: 10.1016/j.amjsurg.2015.05.009.Peer-Reviewed Original ResearchConceptsEarly hospital readmissionHospital readmissionOverall mortalityLong-term mortalitySignificant independent predictorsBaseline group differencesPancreatectomy patientsIndependent predictorsPrognostic significanceInstitutional databaseRisk factorsPancreatectomyMultivariate analysisReadmissionMortalityComplicationsPatientsAdditional studiesGroup differencesStatewide datasetMorbiditySocial factorsTracking Early Readmission After Pancreatectomy to Index and Nonindex Institutions: A More Accurate Assessment of Readmission
Tosoian JJ, Hicks CW, Cameron JL, Valero V, Eckhauser FE, Hirose K, Makary MA, Pawlik TM, Ahuja N, Weiss MJ, Wolfgang CL. Tracking Early Readmission After Pancreatectomy to Index and Nonindex Institutions: A More Accurate Assessment of Readmission. JAMA Surgery 2015, 150: 152-158. PMID: 25535811, PMCID: PMC4461067, DOI: 10.1001/jamasurg.2014.2346.Peer-Reviewed Original ResearchConceptsTertiary care referral centerPatient-level factorsNonindex hospitalEarly readmissionReferral centerMultivariable analysisPatterns of readmissionPostoperative drain placementRate of readmissionRisk of readmissionData of patientsAge 65 yearsHigh-volume institutionsDistal pancreatectomyPostoperative infectionPrimary outcomeLiver diseaseDrain placementInstitutional databaseRisk factorsPancreatectomyRetrospective analysisReadmissionMAIN OUTCOMEPatients
2014
A comparison of open and minimally invasive surgery for hepatic and pancreatic resections using the nationwide inpatient sample
Ejaz A, Sachs T, He J, Spolverato G, Hirose K, Ahuja N, Wolfgang CL, Makary MA, Weiss M, Pawlik TM. A comparison of open and minimally invasive surgery for hepatic and pancreatic resections using the nationwide inpatient sample. Surgery 2014, 156: 538-547. PMID: 25017135, PMCID: PMC4316739, DOI: 10.1016/j.surg.2014.03.046.Peer-Reviewed Original ResearchConceptsMIS patientsInpatient outcomesLiver operationsNationwide Inpatient Sample databasePreoperative medical comorbiditiesIncidence of complicationsMultiple comorbid conditionsShorter median lengthAppropriate International ClassificationNationwide Inpatient SampleInvasive surgery techniquesDuration of stayHospital mortalityPostoperative morbidityHepatic resectionMedical comorbiditiesPancreatic resectionComorbid conditionsMIS groupMedian lengthOpen surgeryInpatient SampleOpen procedureRobotic assistInternational Classification
2013
Assessing Readmission After General, Vascular, and Thoracic Surgery Using ACS-NSQIP
Lucas DJ, Haider A, Haut E, Dodson R, Wolfgang CL, Ahuja N, Sweeney J, Pawlik TM. Assessing Readmission After General, Vascular, and Thoracic Surgery Using ACS-NSQIP. Annals Of Surgery 2013, 258: 430-439. PMID: 24022435, PMCID: PMC4623433, DOI: 10.1097/sla.0b013e3182a18fcc.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDatabases, FactualDecision Support TechniquesFemaleFollow-Up StudiesHealth Status IndicatorsHumansLength of StayMaleMiddle AgedMultivariate AnalysisPatient ReadmissionPostoperative ComplicationsRegression AnalysisRisk FactorsROC CurveSurgical Procedures, OperativeThoracic Surgical ProceduresUnited StatesVascular Surgical ProceduresConceptsASA classReadmission ratesThoracic surgerySurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramInteger-based scoreMedian American SocietyStay 10 daysMedian patient ageRisk of readmissionHigher readmission ratesQuality Improvement ProgramAnesthesiologists classInpatient complicationsMedian LOSPatient agePatient characteristicsNonelective surgeryUpper gastrointestinalACS-NSQIPReadmission riskRisk factorsReadmissionAmerican College
2008
Multilevel Analysis of the Impact of Community vs Patient Factors on Access to Immediate Breast Reconstruction Following Mastectomy in Maryland
Rosson GD, Singh NK, Ahuja N, Jacobs LK, Chang DC. Multilevel Analysis of the Impact of Community vs Patient Factors on Access to Immediate Breast Reconstruction Following Mastectomy in Maryland. JAMA Surgery 2008, 143: 1076-1081. PMID: 19015466, DOI: 10.1001/archsurg.143.11.1076.Peer-Reviewed Original ResearchConceptsRace/ethnicityImmediate reconstructionPatient factorsPatient's neighborhoodMaryland hospital discharge databasePatient race/ethnicityAfrican American race/ethnicityBreast Reconstruction Following MastectomyImmediate reconstruction ratesNinth Revision procedureImmediate breast reconstructionHospital discharge databaseCommunity factorsCommunity-level factorsPublic health policy measuresSame hospitalizationPatient characteristicsPatient demographicsHealth policy measuresNegative associationDischarge databaseFollowing MastectomyBreast reconstructionInpatient careRevision procedures