Targeting the epigenome of pancreatic cancer for therapy: challenges and opportunities
Baretti M, Ahuja N, Azad N. Targeting the epigenome of pancreatic cancer for therapy: challenges and opportunities. Annals Of Pancreatic Cancer 2019, 2: 18-18. DOI: 10.21037/apc.2019.10.01.Peer-Reviewed Original ResearchEpigenetic modulatory drugsEpigenetic alterationsGene expressionImmediate translational implicationsProgression of PAADEpigenetic regulationHeritable differencesEpigenetic abnormalitiesPrimary sequenceTumor microenvironmentNucleosomesEssential roleCurrent knowledgeTranslational applicationsComplex seriesDNATranslational implicationsNew therapeutic approachesExpressionPancreatic adenocarcinomaEpigenomeChromatinEpigeneticsSubsequent interactionAlterations