Histopathologic Basis for the Favorable Survival after Resection of Intraductal Papillary Mucinous Neoplasm-Associated Invasive Adenocarcinoma of the Pancreas
Poultsides GA, Reddy S, Cameron JL, Hruban RH, Pawlik TM, Ahuja N, Jain A, Edil BH, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL. Histopathologic Basis for the Favorable Survival after Resection of Intraductal Papillary Mucinous Neoplasm-Associated Invasive Adenocarcinoma of the Pancreas. Annals Of Surgery 2010, 251: 470-476. PMID: 20142731, PMCID: PMC3437748, DOI: 10.1097/sla.0b013e3181cf8a19.Peer-Reviewed Original ResearchConceptsIntraductal papillary mucinous neoplasmPancreatic ductal adenocarcinomaResection of IPMNsAdverse pathologic characteristicsInvasive pancreatic adenocarcinomaAdvanced T stageLymph node metastasisInvasive adenocarcinomaPancreatic adenocarcinomaFavorable survivalNode metastasisPathologic characteristicsT stageVascular invasionRegional lymph node metastasisFavorable biologic behaviorMicroscopic margin involvementPancreatic resection databasePositive resection marginsCox regression analysisHigh tumor gradePapillary mucinous neoplasmPoor tumor differentiationCurative intentMargin involvement