Genomic approaches in dissecting complex biological pathways
Sun N, Zhao H. Genomic approaches in dissecting complex biological pathways. Pharmacogenomics 2004, 5: 163-179. PMID: 15016608, DOI: 10.1517/phgs.5.2.163.27488.Peer-Reviewed Original ResearchMeSH KeywordsBayes TheoremCluster AnalysisComputational BiologyComputer SimulationGenomicsModels, BiologicalModels, GeneticConceptsNetwork modelScale-free network modelDifferent genomic dataBoolean network modelDifferential equationsScale-free propertyMathematical modelBayesian network modelLarge-scale genomic dataGeneral network propertiesLarge-scale dataData integration methodIntegration methodGenomic dataLocal propertiesComputational methodsNetwork motifsData typesNetwork propertiesRich informationPrior knowledgeDifferent modelsRigorous comparisonEquationsMajor methodologies