2019
Androgens drive microvascular endothelial dysfunction in women with polycystic ovary syndrome: role of the endothelin B receptor
Usselman CW, Yarovinsky T, Steele FE, Leone CA, Taylor HS, Bender JR, Stachenfeld NS. Androgens drive microvascular endothelial dysfunction in women with polycystic ovary syndrome: role of the endothelin B receptor. The Journal Of Physiology 2019, 597: 2853-2865. PMID: 30847930, DOI: 10.1113/jp277756.Peer-Reviewed Original ResearchMeSH KeywordsAdultAndrogensCardiovascular DiseasesDihydrotestosteroneEndothelin-1Endothelium, VascularEstrogensEthinyl EstradiolFemaleGlucose Tolerance TestHumansMicrovesselsNitric OxideObesityPolycystic Ovary SyndromeReceptor, Endothelin BSkinVascular Endothelial Growth Factor AVasodilationYoung AdultConceptsPolycystic ovary syndromeCardiovascular dysfunctionEndothelial dysfunctionOvary syndromeEndothelin-1Endothelial functionNO productionAndrogen receptor-dependent mannerEndothelin-B receptor subtypeCardiovascular risk factorsMicrovascular endothelial dysfunctionMicrovascular endothelial functionCutaneous vascular conductanceB receptor subtypesEndothelin B receptorLaser Doppler flowmetryNitric oxide inhibitionReceptor-dependent mannerEndothelial cell NO productionDose-response curveVasodilating responsePCOS subjectsLean womenObese womenVascular conductance
2013
Androgens influence microvascular dilation in PCOS through ET-A and ET-B receptors
Wenner MM, Taylor HS, Stachenfeld NS. Androgens influence microvascular dilation in PCOS through ET-A and ET-B receptors. AJP Endocrinology And Metabolism 2013, 305: e818-e825. PMID: 23921139, PMCID: PMC3798701, DOI: 10.1152/ajpendo.00343.2013.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeET-B receptorsMicrovascular dilationHeat-induced vasodilationReceptor inhibitionET-B receptor antagonistGonadotropin-releasing hormone antagonistLaser Doppler flowmetryAndrogen suppressionOvary syndromeVascular dysfunctionHealthy womenT administrationEnhanced vasodilationHormone antagonistReceptor antagonistCutaneous microdialysisDoppler flowmetryTestosterone effectsSubtype receptorsVasodilationDay 8WomenDilationGnRHant
1998
Moderate‐Intensity Aerobic Training Improves Glucose Tolerance in Aging Independent of Abdominal Adiposity
DiPietro L, Seeman T, Stachenfeld N, Katz L, Nadel E. Moderate‐Intensity Aerobic Training Improves Glucose Tolerance in Aging Independent of Abdominal Adiposity. Journal Of The American Geriatrics Society 1998, 46: 875-879. PMID: 9670875, DOI: 10.1111/j.1532-5415.1998.tb02722.x.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAgedAgingBlood GlucoseExerciseExercise TherapyFatty Acids, NonesterifiedFemaleGlucose Tolerance TestHumansInsulinMaleMultivariate AnalysisObesityConceptsOral glucose tolerance testModerate-intensity aerobic trainingAbdominal adiposityGlucose toleranceInsulin responseAerobic trainingFree fatty acidsAbdominal fatT groupImpaired glucose toleranceHealthy older menSerum insulin responseGlucose tolerance testAerobic training programGlucose response curveTolerance testIncremental areaPlasma glucoseGlucose curveVO2 peakAcademic medical institutionsOlder menControl groupGlucose responseAdiposity