2022
Are there sex differences in risk for exertional heat stroke? A translational approach
Giersch GEW, Garcia CK, Stachenfeld N, Charkoudian N. Are there sex differences in risk for exertional heat stroke? A translational approach. Quarterly Journal Of Experimental Physiology And Cognate Medical Sciences 2022, 107: 1136-1143. PMID: 35598159, DOI: 10.1113/ep090402.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBody Temperature RegulationFemaleGonadal Steroid HormonesHeat Stress DisordersHeat StrokeHumansMaleSex CharacteristicsConceptsExertional heat strokeHeat strokeRisk factorsTranslational approachCentral nervous system dysfunctionNervous system dysfunctionFemale sex hormonesSex differencesHuman researchOrgan damageFatal conditionSystem dysfunctionSex hormonesPhysical activityStrokeTranslational modelOccupational workersRiskMilitary personnelAnimalsTreatmentHuman modelReviewFuture investigationsPhysiological differences
2020
Menstrual cycle and thermoregulation during exercise in the heat: A systematic review and meta-analysis
Giersch GEW, Morrissey MC, Katch RK, Colburn AT, Sims ST, Stachenfeld NS, Casa DJ. Menstrual cycle and thermoregulation during exercise in the heat: A systematic review and meta-analysis. Journal Of Science And Medicine In Sport 2020, 23: 1134-1140. PMID: 32499153, DOI: 10.1016/j.jsams.2020.05.014.Peer-Reviewed Original ResearchMeSH KeywordsBody Temperature RegulationExerciseFemaleFollicular PhaseHot TemperatureHumansLuteal PhaseMenstrual CycleConceptsSystematic reviewHeart rateSweat rateSkin temperatureMenstrual cycle phaseMenstrual cycle variationsAerobic exerciseFollicular phaseMenstrual cycleLuteal phaseInclusion criteriaMenstrual phaseLimited available dataMean skin temperatureEffect size estimatesSignificant differencesBody temperatureEffect sizeExerciseWomenCycle phaseInternal body temperatureReviewTotal number
2015
Sex hormone effects on autonomic mechanisms of thermoregulation in humans
Charkoudian N, Stachenfeld N. Sex hormone effects on autonomic mechanisms of thermoregulation in humans. Autonomic Neuroscience 2015, 196: 75-80. PMID: 26674572, DOI: 10.1016/j.autneu.2015.11.004.ChaptersMeSH KeywordsAnimalsBody TemperatureBody Temperature RegulationGonadal Steroid HormonesHumansSex FactorsSkinSweatingConceptsAutonomic mechanismsReproductive hormonesBody temperatureCentral autonomic nucleusHeat dissipation responsePolycystic ovary syndromeFemale reproductive hormonesPeripheral blood vesselsInfluence of progesteroneSkin blood flowAutonomic nucleiOvary syndromePeripheral effectsMenstrual cycleHormone levelsBlood flowHormone effectsLow body temperatureBlood vesselsEstrogenHigh body temperatureRecent evidenceMenopauseProgesteroneThermoregulatory responses
2014
The Interrelationship of Research in the Laboratory and the Field to Assess Hydration Status and Determine Mechanisms Involved in Water Regulation During Physical Activity
Stachenfeld NS. The Interrelationship of Research in the Laboratory and the Field to Assess Hydration Status and Determine Mechanisms Involved in Water Regulation During Physical Activity. Sports Medicine 2014, 44: 97-104. PMID: 24791921, PMCID: PMC4008811, DOI: 10.1007/s40279-014-0155-0.Commentaries, Editorials and LettersMeSH KeywordsBody Temperature RegulationBody WaterDehydrationDrinkingExerciseHumansHyponatremiaPerceptionPhysical Education and TrainingRegional Blood FlowSkinThirstReproductive Hormone Influences on Thermoregulation in Women
Charkoudian N, Stachenfeld NS. Reproductive Hormone Influences on Thermoregulation in Women. 2014, 4: 793-804. PMID: 24715568, DOI: 10.1002/cphy.c130029.ChaptersConceptsReproductive hormonesHormone exposurePeripheral thermal informationReproductive hormone effectsMale reproductive hormonesBody temperatureThermoregulatory responsesProgesterone/progestinsPeripheral mechanismsAnterior hypothalamusPreoptic areaHormone influenceHormone effectsLow body temperatureBody heatingYoung womenThermoregulatory controlEnvironmental exposuresWomenHormoneMajor quantitative differencesProgestinsAndrogensEstrogenPhysiological thermoregulatory responses
2010
Greater Exercise Sweating in Obese Women with Polycystic Ovary Syndrome Compared with Obese Controls
STACHENFELD NS, YECKEL CW, TAYLOR HS. Greater Exercise Sweating in Obese Women with Polycystic Ovary Syndrome Compared with Obese Controls. Medicine & Science In Sports & Exercise 2010, 42: 1660-1668. PMID: 20195177, PMCID: PMC3109293, DOI: 10.1249/mss.0b013e3181d8cf68.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromePCOS groupOvary syndromeControl groupGonadotropin-releasing hormone antagonistObese controlsObese womenAge-predicted HRmaxCore temperature thresholdHormone antagonistTestosterone effectsDay 4GnRHantSweat volumeDay 13Total sweat lossHormone conditionsWomenSweatingE2Sweat lossSyndromeEstradiolTestosteroneThermoregulatory responses