2017
A translational approach for NMDA receptor profiling as a vulnerability biomarker for depression and schizophrenia
Gunduz‐Bruce H, Kenney J, Changlani S, Peixoto A, Gueorguieva R, Leone C, Stachenfeld N. A translational approach for NMDA receptor profiling as a vulnerability biomarker for depression and schizophrenia. Quarterly Journal Of Experimental Physiology And Cognate Medical Sciences 2017, 102: 587-597. PMID: 28294453, DOI: 10.1113/ep086212.Peer-Reviewed Original ResearchMeSH KeywordsAdultArginine VasopressinBiomarkersDepressionFemaleHumansMaleOsmolar ConcentrationReceptors, N-Methyl-D-AspartateSaline Solution, HypertonicSchizophreniaWater-Electrolyte BalanceConceptsSubgroup of patientsHealthy control subjectsNMDA receptorsControl subjectsDepressed patientsAVP releaseAnimal studiesSchizophrenic subjectsTranslational approachVivo evidenceRecent clinical trialsNMDA receptor functionPlasma arginine vasopressin concentrationNMDA receptor activityHypertonic saline infusionNMDA antagonist ketamineArginine vasopressin concentrationHypertonic salineInverse associationClinical trialsHealthy controlsSaline infusionGlutamate signalingSchizophrenic patientsVasopressin concentration
2008
Sex Hormone Effects on Body Fluid Regulation
Stachenfeld NS. Sex Hormone Effects on Body Fluid Regulation. Exercise And Sport Sciences Reviews 2008, 36: 152-159. PMID: 18580296, PMCID: PMC2849969, DOI: 10.1097/jes.0b013e31817be928.Peer-Reviewed Original ResearchMeSH KeywordsArginine VasopressinBody FluidsEstradiolFemaleGonadotropin-Releasing HormoneHomeostasisHumansLeuprolideMaleProgesteroneSaline Solution, HypertonicSodiumThirstWater-Electrolyte Balance
1998
Estrogen influences osmotic secretion of AVP and body water balance in postmenopausal women
Stachenfeld N, Dipietro L, Palter S, Nadel E. Estrogen influences osmotic secretion of AVP and body water balance in postmenopausal women. American Journal Of Physiology 1998, 274: r187-r195. PMID: 9458917, DOI: 10.1152/ajpregu.1998.274.1.r187.Peer-Reviewed Original ResearchConceptsMin of drinkingPg/Body water balanceHypertonic salineFractional sodium excretionPlasma aldosterone concentrationRenal sodium reabsorptionFree water clearancePlasma estradiol concentrationsHypertonic saline infusionHigh E2 statesWater ad libitumMosmol/kgH2OAldosterone concentrationPostmenopausal womenSodium excretionPlacebo administrationUrine outputAVP secretionSodium reabsorptionFluid retentionE2 treatmentEstradiol concentrationsWater clearanceSaline infusion
1996
Thirst and fluid regulatory responses to hypertonicity in older adults
Stachenfeld N, Mack G, Takamata A, DiPietro L, Nadel E. Thirst and fluid regulatory responses to hypertonicity in older adults. American Journal Of Physiology 1996, 271: r757-r765. PMID: 8853401, DOI: 10.1152/ajpregu.1996.271.3.r757.Peer-Reviewed Original Research
1995
Body temperature modification of osmotically induced vasopressin secretion and thirst in humans
Takamata A, Mack G, Stachenfeld N, Nadel E. Body temperature modification of osmotically induced vasopressin secretion and thirst in humans. American Journal Of Physiology 1995, 269: r874-r880. PMID: 7485606, DOI: 10.1152/ajpregu.1995.269.4.r874.Peer-Reviewed Original Research