2007
Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women
Stachenfeld NS, Taylor HS. Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women. Clinical Endocrinology 2007, 66: 410-418. PMID: 17302877, DOI: 10.1111/j.1365-2265.2007.02748.x.Peer-Reviewed Original ResearchConceptsExtracellular fluid volumeTranscapillary albumin escape rateGonadotropin-releasing hormone antagonistPmol/Plasma renin activitySerum aldosterone concentrationHealthy young womenAlbumin escape rateRenin activityAldosterone concentrationGnRH antagonistHealthy womenProgesterone administrationExogenous oestradiolIntravascular volumeHormone antagonistProgesterone increaseDay 2Day 5Hormone treatmentOestradiolDay 13Extravascular componentOncotic pressureYoung women
2004
Responses to a Saline Load in Gonadotropin-Releasing Hormone Antagonist-Pretreated Premenopausal Women Receiving Progesterone or Estradiol-Progesterone Therapy
Stachenfeld NS, Keefe DL, Taylor HS. Responses to a Saline Load in Gonadotropin-Releasing Hormone Antagonist-Pretreated Premenopausal Women Receiving Progesterone or Estradiol-Progesterone Therapy. The Journal Of Clinical Endocrinology & Metabolism 2004, 90: 386-394. PMID: 15486051, DOI: 10.1210/jc.2004-0941.Peer-Reviewed Original ResearchConceptsSodium regulationOvarian hyperstimulation syndromeEffects of estradiolMin of restImportant clinical implicationsHyperstimulation syndromeSodium excretionGnRH antagonistRenal diseaseSodium loadIsotonic salineClinical implicationsSyndromeReproductive syndromeSubjectsPreeclampsiaGnRHGroupEstradiolProgesteroneAntagonistExcretionDiseaseAdministrationSaline
2001
Selected Contribution: Sex differences in osmotic regulation of AVP and renal sodium handling
Stachenfeld N, Splenser A, Calzone W, Taylor M, Keefe D. Selected Contribution: Sex differences in osmotic regulation of AVP and renal sodium handling. Journal Of Applied Physiology 2001, 91: 1893-1901. PMID: 11568177, DOI: 10.1152/jappl.2001.91.4.1893.Peer-Reviewed Original ResearchConceptsSystolic blood pressureBlood pressureMenstrual phaseBasal plasma AVP concentrationGreater systolic blood pressurePressure-natriuresis curveRenal sodium handlingPlasma osmolalityPlasma AVP concentrationMin of restMidluteal menstrual phasesBasal plasma osmolalitySex differencesSodium handlingPulse pressureBody wtAVP concentrationAVP releaseNaCl infusionHormone responseMenWomenGreater sensitivityBody waterOsmolality
1999
Physiological variability of fluid-regulation hormones in young women
Stachenfeld N, DiPietro L, Kokoszka C, Silva C, Keefe D, Nadel E. Physiological variability of fluid-regulation hormones in young women. Journal Of Applied Physiology 1999, 86: 1092-1096. PMID: 10066728, DOI: 10.1152/jappl.1999.86.3.1092.Peer-Reviewed Original ResearchConceptsPlasma renin activityEarly follicular phaseFollicular phaseMenstrual phaseMenstrual phase-related differencesAtrial natriuretic peptideDifferent menstrual phasesMean hormone concentrationsRenin activityNatriuretic peptideMidluteal phaseMenstrual cycleHormonal variablesPlasma concentrationsLuteal phaseHormone concentrationsPhase-related differencesYoung womenHormoneCronbach's alphaRehydration periodRestingAlphaMean concentrationPhysiological variability
1996
Fluid balance and renal response following dehydrating exercise in well-trained men and women
Stachenfeld N, Gleim G, Zabetakis P, Nicholas J. Fluid balance and renal response following dehydrating exercise in well-trained men and women. European Journal Of Applied Physiology 1996, 72: 468-477. PMID: 8925818, DOI: 10.1007/bf00242277.Peer-Reviewed Original ResearchConceptsPlasma renin activityEnd of exerciseSodium handlingMin postexerciseEarly recoveryFluid balanceLow plasma renin activityRenal free water clearancePlasma volumeFractional sodium excretionPlasma osmolalityFree water clearanceOverall fluid balanceMin of recoveryFluid-regulating hormonesRenin activitySodium excretionSerum aldosteroneNorepinephrine concentrationsRenal responseWater clearanceRenal waterAnaerobic thresholdWater reabsorptionWomen
1995
Body temperature modification of osmotically induced vasopressin secretion and thirst in humans
Takamata A, Mack G, Stachenfeld N, Nadel E. Body temperature modification of osmotically induced vasopressin secretion and thirst in humans. American Journal Of Physiology 1995, 269: r874-r880. PMID: 7485606, DOI: 10.1152/ajpregu.1995.269.4.r874.Peer-Reviewed Original Research