Mechanism of attenuated thirst in aging: role of central volume receptors
Stachenfeld N, DiPietro L, Nadel E, Mack G. Mechanism of attenuated thirst in aging: role of central volume receptors. American Journal Of Physiology 1997, 272: r148-r157. PMID: 9039003, DOI: 10.1152/ajpregu.1997.272.1.r148.Peer-Reviewed Original ResearchConceptsCentral blood volume expansionBlood volume expansionYoung subjectsOlder subjectsPlasma volumePlasma atrial natriuretic peptide concentrationAtrial natriuretic peptide concentrationsThirst ratingsOlder peopleFractional sodium excretionPlasma renin activityArterial blood pressureNatriuretic peptide concentrationsCentral volume expansionMin of headWater perfusion suitAd libitum water intakeAldosterone concentrationRenin activitySodium excretionArterial baroreceptorsArterial pressureBlood pressureRenal responseVolume receptors