2020
Pathophysiological effects of androgens on the female vascular system
Stone T, Stachenfeld NS. Pathophysiological effects of androgens on the female vascular system. Biology Of Sex Differences 2020, 11: 45. PMID: 32727622, PMCID: PMC7391603, DOI: 10.1186/s13293-020-00323-6.ChaptersConceptsFemale cardiovascular systemPolycystic ovary syndromeFemale vasculatureHormone therapyOvary syndromePathophysiological effectsCardiovascular systemTransgender menPrimary medical interventionSignificant medical risksHigh blood pressureCardiovascular disease statesEffects of testosteroneEndogenous androgen concentrationsSex differencesPotential causative linkChronic hyperandrogenismTestosterone dosesEndothelial dysfunctionBlood pressurePatient groupVascular functionCardiovascular regulationSex hormonesAndrogen receptor
2018
Blood pressure predicts endothelial function and the effects of ethinyl estradiol exposure in young women
Adler TE, Usselman CW, Takamata A, Stachenfeld NS. Blood pressure predicts endothelial function and the effects of ethinyl estradiol exposure in young women. AJP Heart And Circulatory Physiology 2018, 315: h925-h933. PMID: 29906227, DOI: 10.1152/ajpheart.00188.2018.Peer-Reviewed Original ResearchMeSH KeywordsAdiposityAdministration, OralAdolescentAdultAntihypertensive AgentsArterial PressureBrachial ArteryDrug Administration ScheduleEndothelium, VascularEthinyl EstradiolExercise TestFemaleHand StrengthHumansHypertensionIschemiaObesityTime FactorsTreatment OutcomeVasodilator AgentsYoung AdultConceptsEthinyl estradiol administrationEndothelial functionBlood pressureEstradiol administrationEthinyl estradiol exposureEndothelial dysfunctionShear stress stimulusEndothelial impairmentEstradiol exposureHBP groupExercise responseNBP groupFlow-mediated dilation responseHigh blood pressure groupYoung womenIschemic handgrip exerciseOral ethinyl estradiolOvert cardiovascular dysfunctionBlood pressure groupFlow-mediated dilationNormal blood pressureHigh blood pressureMild hypertensionFMD responseHandgrip exerciseBlood Pressure Predicts Endothelial Function and Effect of Ethinyl Estradiol in Young Obese and Lean Women
Adler T, Usselman C, Takamata A, Stachenfeld N. Blood Pressure Predicts Endothelial Function and Effect of Ethinyl Estradiol in Young Obese and Lean Women. The FASEB Journal 2018, 32: 713.3-713.3. DOI: 10.1096/fasebj.2018.32.1_supplement.713.3.Peer-Reviewed Original ResearchElevated blood pressureHigh blood pressureBlood pressureEndothelial functionEthinyl estradiol treatmentEndothelial dysfunctionFMD responseHealthy womenEstradiol treatmentAmerican Heart Association guidelinesNew American Heart Association guidelinesIschemic handgrip exerciseHeart Association guidelinesYoung healthy womenFull-text articlesShear stress stimulusRH-FMDMild hypertensionHandgrip exerciseLean womenVasodilatory responseHyperemic responseAssociation guidelinesCardiovascular diseaseEthinyl estradiol