2011
Sex differences in endothelial function in the microvasculature: effects of PCOS
Stachenfeld N, Wenner M, Taylor H. Sex differences in endothelial function in the microvasculature: effects of PCOS. The FASEB Journal 2011, 25: 837.2-837.2. DOI: 10.1096/fasebj.25.1_supplement.837.2.Peer-Reviewed Original ResearchPolycystic ovary syndromeETB receptorsEffects of PCOSHeart disease riskLaser Doppler flowmetrySkin blood flowNormal reproductive functionDose-response curveEndothelial dysfunctionOvary syndromeVasoconstrictive responseVasodilatory responseEndothelial functionCutaneous microvasculatureETA receptorsHealthy womenAntagonist infusionDoppler flowmetrySmooth muscleBlood flowReceptor AReproductive functionDisease riskWomenReceptors
2010
Peripheral microvascular responses to norepinephrine in women with orthostatic intolerance
Wenner M, Taylor H, Stachenfeld N. Peripheral microvascular responses to norepinephrine in women with orthostatic intolerance. The FASEB Journal 2010, 24: 991.17-991.17. DOI: 10.1096/fasebj.24.1_supplement.991.17.Peer-Reviewed Original ResearchCumulative stress indexVasoconstrictor responsesAdrenergic responseMaximal lower body negative pressureLower body negative pressurePeripheral microvascular responseEffects of estradiolBody negative pressureFemale sex hormonesSkin blood flowEndogenous E2GnRH antagonistNE infusionDaily administrationMicrovascular responsesCutaneous microvasculatureOrthostatic intoleranceOrthostatic toleranceSex hormonesBlood flowSkin microvasculatureAdrenergic stimulationDay 4Hormone treatmentDay 13