2023
Association between intraprocedural drops in blood pressure and infarct growth rate patterns after acute large-vessel occlusions
Galecio-Castillo M, Quispe-Orozco D, Farooqui M, Dajles A, Vivanco-Suarez J, Rodriguez-Calienes A, Prasad A, Begunova L, Petersen N, Ortega-Gutierrez S. Association between intraprocedural drops in blood pressure and infarct growth rate patterns after acute large-vessel occlusions. Journal Of NeuroInterventional Surgery 2023, jnis-2023-020899. PMID: 37923382, PMCID: PMC11271969, DOI: 10.1136/jnis-2023-020899.Peer-Reviewed Original ResearchRelative cerebral blood flowInfarct growth ratesFinal infarct volumeHypoperfusion intensity ratioAlberta Stroke Program Early CT ScoreMedian arterial pressureDiffusion-weighted imaging (DWI) magnetic resonance imagingCerebral infarction 2Modified Rankin scoreLarge vessel occlusionEndovascular therapyInfarct volumeStroke onsetBlood pressureAcute large vessel occlusionHealth Stroke Scale scoreStroke Scale scoreAcute ischemic strokeCohort observational studySubgroup of patientsCerebral blood flowBlood pressure dropLVO-AISRankin scoreInfarct growth
2019
Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage
Silverman A, Kodali S, Strander S, Gilmore EJ, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth KN, Petersen NH. Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage. Stroke 2019, 50: 2729-2737. PMID: 31495332, PMCID: PMC6756936, DOI: 10.1161/strokeaha.119.026282.Peer-Reviewed Original ResearchConceptsLimits of autoregulationAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageFunctional outcomeArterial pressureIntracranial pressureBP targetsWorse outcomesPercent timeBlood pressure targetsBlood pressure managementMean arterial pressureModified Rankin ScalePotential neuroprotective strategiesWorse functional outcomePoor functional outcomeCerebral blood flowMultivariate logistic regressionTotal monitoring periodAutoregulatory indexPressure targetsCerebral ischemiaNeuroprotective strategiesRankin ScaleCerebral autoregulation
2017
Multimodality Monitoring
Cassa R, Petersen N. Multimodality Monitoring. 2017, 363-385. DOI: 10.1007/978-3-319-48669-7_20.Peer-Reviewed Original ResearchMultimodality monitoringBrain injuryJugular venous oxygen saturationAdditional brain injuryBrain tissue hypoxiaAcute brain injuryNon-convulsive seizuresVenous oxygen saturationBrain tissue oxygenationCerebral blood flowCerebral microdialysisQuantitative EEG measuresCerebral ischemiaIntracranial hypertensionSubclinical changesDelivery of oxygenVulnerable brainTissue hypoxiaIntracranial pressureOxygen saturationPathologic eventsBlood flowTissue oxygenationPhysiologic parametersMetabolic changes
2015
Dynamic Cerebral Autoregulation Is Transiently Impaired for One Week after Large-Vessel Acute Ischemic Stroke
Petersen NH, Ortega-Gutierrez S, Reccius A, Masurkar A, Huang A, Marshall RS. Dynamic Cerebral Autoregulation Is Transiently Impaired for One Week after Large-Vessel Acute Ischemic Stroke. Cerebrovascular Diseases 2015, 39: 144-150. PMID: 25661277, PMCID: PMC4754197, DOI: 10.1159/000368595.Peer-Reviewed Original ResearchConceptsDynamic cerebral autoregulationLarge-vessel ischemic strokeUnaffected hemisphereAffected hemisphereIschemic strokeCerebral autoregulationBlood pressureAcute large-vessel ischemic strokeLarge vessel acute ischemic strokeAcute blood pressure managementMiddle cerebral artery territoryAcute ischemic strokeBlood pressure managementCerebral blood flowBlood flow velocityDay strokePoor autoregulationAcute strokeArtery territoryArterial catheterTranscranial DopplerAffected sideUnaffected sideControl subjectsHealthy controls
2014
Comparison of non-invasive and invasive arterial blood pressure measurement for assessment of dynamic cerebral autoregulation.
Petersen NH, Ortega-Gutierrez S, Reccius A, Masurkar A, Huang A, Marshall RS. Comparison of non-invasive and invasive arterial blood pressure measurement for assessment of dynamic cerebral autoregulation. Neurocritical Care 2014, 20: 60-8. PMID: 24452959, DOI: 10.1007/s12028-013-9949-4.Peer-Reviewed Original ResearchConceptsDynamic cerebral autoregulationAssessment of DCAAcute brain injuryBlood pressure monitoringBlood pressure measurementsCerebral autoregulationBrain injuryPressure monitoringInvasive arterial blood pressure measurementsInvasive arterial blood pressure monitoringGood inter-method agreementArterial blood pressure monitoringCerebral blood flow velocityArterial blood pressure measurementsDirect intravascular measurementMean velocity indexMean patient ageArterial blood pressureRadial artery catheterCerebral blood flowMonitoring of patientsBlood flow velocityBlood pressure methodDCA assessmentArtery catheter