Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis
Shapiro DM, Mandava G, Yalcin SE, Arranz-Gibert P, Dahl PJ, Shipps C, Gu Y, Srikanth V, Salazar-Morales AI, O’Brien J, Vanderschuren K, Vu D, Batista VS, Malvankar NS, Isaacs FJ. Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis. Nature Communications 2022, 13: 829. PMID: 35149672, PMCID: PMC8837800, DOI: 10.1038/s41467-022-28206-x.Peer-Reviewed Original ResearchConceptsProtein nanowiresElectronic functionalityChemical-based synthesisConductive protein nanowiresSequence-controlled synthesisHigh electronic conductivityGold nanoparticlesSite-specific conjugationSynthetic chemistryTunable functionalityElectronic conductivityTunable propertiesAttractive biomaterialNonstandard amino acidsSynthetic biologyNanowiresBiomaterialsProtein materialSynthesisAtomic structureMost biomaterialsIncorporation of tryptophanFunctionalityConductivityNanoparticles