Chemical shift mapping of γδ resolvase dimer and activated tetramer: Mechanistic implications for DNA strand exchange
Gehman J, Cocco M, Grindley N. Chemical shift mapping of γδ resolvase dimer and activated tetramer: Mechanistic implications for DNA strand exchange. Biochimica Et Biophysica Acta 2008, 1784: 2086-2092. PMID: 18840551, DOI: 10.1016/j.bbapap.2008.08.023.Peer-Reviewed Original ResearchConceptsDNA strand exchangeStrand exchangeChemical shift mappingWild-type dimerNMR chemical shift assignmentsChemical shift assignmentsDNA recombinaseResolvase dimersX-ray diffraction modelSequence regionsSubunit interfaceTetrameric stateProtomer-protomer interactionsGammadelta resolvaseShift mappingShift assignmentsMechanistic hypothesesStructural variationsResidues