Host Cell Amplification of Nutritional Stress Contributes To Persistence in Chlamydia trachomatis
Pokorzynski N, Alla M, Carabeo R. Host Cell Amplification of Nutritional Stress Contributes To Persistence in Chlamydia trachomatis. MBio 2022, 13: e02719-22. PMID: 36377897, PMCID: PMC9765610, DOI: 10.1128/mbio.02719-22.Peer-Reviewed Original ResearchConceptsHost cell responsesInfected host cellsNutritional stressStress responseIntracellular environmentGTP biosynthesisHost cellsUniversal stress responseTranscriptional stress responseDual RNA sequencingConsequence of coevolutionEssential nutrient ironBacterial stress responseStress response mechanismsChlamydial growthGuanine nucleotide synthesisGenome reductionTryptophan starvationEukaryotic hostsIron starvationInfected epithelial cellsRNA sequencingNutrient ironIron limitationDistinct nutrients