BIOM-05. THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH SOLID TUMOR LEPTOMENINGEAL METASTASIS
Kumthekar P, Youssef M, Blondin N, Azadi A, Piccioni D, Glantz M, Carillo J, Sharma A, Avgeropoulos N, Makar S, Blouw B, Natasha A, Fisher D, Huynh L, Peters J, Matsutani M, Sales E, Sweed N, Dugan M, Kesari S. BIOM-05. THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH SOLID TUMOR LEPTOMENINGEAL METASTASIS. Neuro-Oncology 2022, 24: vii4-vii5. DOI: 10.1093/neuonc/noac209.015.Peer-Reviewed Original ResearchNon-small cell lung cancerUpper GI cancerLeptomeningeal metastasesHER2 amplificationPrimary tumorBreast cancerLM patientsGI cancersCancer patientsHER2-positive primary breast cancerHER2-positive primary tumorsSolid-tumor leptomeningeal metastasisUpper GI cancer patientsCSF tumor cellsGI cancer patientsPositive primary tumorsPrimary breast cancerBreast cancer patientsCell lung cancerIT trastuzumabLM tumorsNSCL cancerNSCLC patientsUpper GIClinical benefit