The AE gene family of Cl/HCO3- exchangers.
Alper SL, Darman RB, Chernova MN, Dahl NK. The AE gene family of Cl/HCO3- exchangers. Journal Of Nephrology 2002, 15 Suppl 5: s41-53. PMID: 12027221.Peer-Reviewed Original ResearchConceptsN-terminal cytoplasmic domainGene familyCytoplasmic domainExchanger geneAcid-base transportMajor intrinsic proteinSLC4 gene familyAE1 anion exchangerStructure-function studiesAE gene familyAnion exchanger geneIndependent anion exchangersIntrinsic proteinsTransmembrane domainTransepithelial acid-base transportRegulatory cell volume increaseRecombinant proteinsAE1 geneSystemic acid-base balanceRegulatory propertiesPoint mutationsBicarbonate cotransporterGenesCl/HCO3 exchangerNoncontiguous regions