2011
Understanding the Role of Natural Killer T Cells in Hematologic Malignancies: Progress and Challenges
Neparidze N, Dhodapkar M. Understanding the Role of Natural Killer T Cells in Hematologic Malignancies: Progress and Challenges. Cancer Drug Discovery And Development 2011, 153-167. DOI: 10.1007/978-1-4614-0613-6_9.Peer-Reviewed Original ResearchNatural killer T cellsKiller T cellsNKT cellsHematologic malignanciesT cellsImportant effector cellsPreliminary clinical studyAnti-tumor effectsNKT functionDendritic cellsTumor immunityEffector cellsHematologic tumorsClinical studiesMalignancyQualitative defectsPatientsCD1dType IAttractive targetCellsVivoClinicNKTTumors
2009
Harnessing CD1d‐Restricted T Cells toward Antitumor Immunity in Humans
Neparidze N, Dhodapkar MV. Harnessing CD1d‐Restricted T Cells toward Antitumor Immunity in Humans. Annals Of The New York Academy Of Sciences 2009, 1174: 61-67. PMID: 19769737, PMCID: PMC2782771, DOI: 10.1111/j.1749-6632.2009.04931.x.Peer-Reviewed Original ResearchConceptsNKT cellsT cellsAntitumor immunityType I NKT cellsType II NKT cellsNatural killer T cellsPresence of CD1dI NKT cellsKiller T cellsAdvanced myelomaNKT activationDendritic cellsImmune therapyAlpha-GalactosylceramideCancer patientsCD1d moleculesLipid antigensPreclinical studiesThalidomide analoguesCD1dDistinct subsetsAgonist ligandsPatientsCancerType I