T Helper 1 (TH1) Functional Phenotype of Human Myelin Basic Protein-Specific T Lymphocytes
Voskuhl R, Martin R, Bergman C, Dalal M, Ruddle N, Mcfarland H. T Helper 1 (TH1) Functional Phenotype of Human Myelin Basic Protein-Specific T Lymphocytes. Autoimmunity 1993, 15: 137-143. PMID: 7692995, DOI: 10.3109/08916939309043888.Peer-Reviewed Original ResearchConceptsExperimental allergic encephalomyelitisMyelin basic proteinMultiple sclerosisT cell linesT cellsMyelin basic protein-specific T lymphocytesMBP-specific T cell linesMurine experimental allergic encephalomyelitisMBP-specific T cellsAntigen-specific cytotoxic activityFunctional phenotypeEncephalitogenic T cellsHuman T cell lineCell linesTh1 subtypeCandidate autoantigenAllergic encephalomyelitisAutoimmune diseasesInflammatory cellsTumor necrosisT lymphocytesInterleukin-4Animal modelsImmunodominant regionCurrent report