2022
Should Corticosteroids Be Used to Treat Biopsy-Proven Drug-Induced Acute Interstitial Nephritis?: PRO
Donati A, Krishnan N. Should Corticosteroids Be Used to Treat Biopsy-Proven Drug-Induced Acute Interstitial Nephritis?: PRO. Kidney360 2022, 3: 1306-1309. PMID: 36176666, PMCID: PMC9416830, DOI: 10.34067/kid.0006642021.Peer-Reviewed Original Research
2015
Drug-induced acute interstitial nephritis: pathology, pathogenesis, and treatment.
Krishnan N, Perazella MA. Drug-induced acute interstitial nephritis: pathology, pathogenesis, and treatment. Iranian Journal Of Kidney Diseases 2015, 9: 3-13. PMID: 25599729.BooksConceptsDrug-induced acute interstitial nephritisCell-mediated immune injuryLess chronic kidney diseaseAcute interstitial nephritisHallmark pathologic featureIncomplete renal recoveryInterstitial dendritic cellsNeo-antigen formationPredominance of CD4Acute kidney injurySerum creatinine levelsChronic kidney diseaseMainstay of treatmentRenal tubular epithelial cellsUse of steroidsDuration of injuryTubular epithelial cellsRenal recoveryChronic dialysisKidney injuryCreatinine levelsImmunologic injuryInterstitial inflammationDendritic cellsImmune injury