A Mutation in the Mouse Chd2 Chromatin Remodeling Enzyme Results in a Complex Renal Phenotype
Marfella CG, Henninger N, LeBlanc SE, Krishnan N, Garlick DS, Holzman LB, Imbalzano AN. A Mutation in the Mouse Chd2 Chromatin Remodeling Enzyme Results in a Complex Renal Phenotype. Kidney & Blood Pressure Research 2008, 31: 421-432. PMID: 19142019, PMCID: PMC2818461, DOI: 10.1159/000190788.Peer-Reviewed Original ResearchConceptsChd2 proteinATP-dependent chromatin remodelingChromodomain helicase DNA-binding protein 2DNA-binding protein 2Family of enzymesChromatin remodelingChromatin structureEpigenetic regulatorsGlomerular diseaseGene expressionMolecular mechanismsKidney functionProtein 2Enzyme resultsDiverse groupProteinNew insightsMutationsRenal phenotypeKidney failureGlomerular functionHematocrit levelsNew moleculesSerum analysisMice