Featured Publications
Endometriosis Pain Management: a Review
Carlyle D, Khader T, Lam D, Vadivelu N, Shiwlochan D, Yonghee C. Endometriosis Pain Management: a Review. Current Pain And Headache Reports 2020, 24: 49. PMID: 32671581, DOI: 10.1007/s11916-020-00884-6.Peer-Reviewed Original ResearchConceptsSurgical managementGnRH agonists/antagonistsNonsteroidal anti-inflammatory drugsPain management optionsAnti-inflammatory drugsAgonists/antagonistsNerve ablationPresacral neurectomyMedical managementTreatment modalitiesAromatase inhibitorsChallenging diseaseSurgical techniqueReviewThe purposeNeurectomyExperimental pharmaceuticalsManagement optionsAblationHysterectomyOophorectomyEndometriosisRegimensResectionDanazolPatients
2013
Common misconceptions about opioid use for pain management at the end of life.
Berger JM, Vadivelu N. Common misconceptions about opioid use for pain management at the end of life. The AMA Journal Of Ethic 2013, 15: 403-9. PMID: 23680560, DOI: 10.1001/virtualmentor.2013.15.5.ecas1-1305.Peer-Reviewed Original Research
2011
Peripheral opioid receptor agonists for analgesia: a comprehensive review.
Vadivelu N, Mitra S, Hines RL. Peripheral opioid receptor agonists for analgesia: a comprehensive review. Journal Of Opioid Management 2011, 7: 55-68. PMID: 21434585, DOI: 10.5055/jom.2011.0049.Peer-Reviewed Original ResearchConceptsPeripheral opioid receptorsOpioid receptor agonistsOpioid receptorsReceptor agonistOpioid analgesiaPeripheral opioid receptor agonistDelta-opioid receptor agonistPhase I clinical trialPeripheral opioid agonistPeripheral opioid analgesiaDorsal root gangliaObvious theoretical advantagesOpioid agonist activityPeripheral muAfferent nervesAfferent neuronsOpioid analgesicsPeripheral terminalsCentral actionOpioid agonistsAntidiarrheal drugsOpioidergic systemRoot gangliaClinical trialsPeripheral tissues
2009
Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements
Dabu-Bondoc S, Vadivelu N, Benson J, Perret D, Kain ZN. Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements. Anesthesia & Analgesia 2009, 110: 208-210. PMID: 19861358, DOI: 10.1213/ane.0b013e3181bea424.Peer-Reviewed Original ResearchConceptsPerioperative analgesic requirementsAnalgesic requirementsGeneral anesthesiaTreatment groupsVisual analog scale scoreIntraoperative analgesic requirementsIntraoperative fentanyl consumptionPostoperative pain scoresAnalog scale scoreFentanyl consumptionPain scoresSurgical outpatientsScale scoreControl groupAnesthesiaMusic groupScoresGroupSubjectsVecuroniumOutpatientsLOW‐DOSE KETAMINE AS AN ADJUNCT TO ROUTINE PAIN PRACTICE: ARE WE READY YET?
Souzdalnitski D, Vadivelu N, Chung KS. LOW‐DOSE KETAMINE AS AN ADJUNCT TO ROUTINE PAIN PRACTICE: ARE WE READY YET? Pain Practice 2009, 9: 405-406. PMID: 19740273, DOI: 10.1111/j.1533-2500.2009.00302.x.Peer-Reviewed Original ResearchPain Quality Assessment Scale: Practical Implications of Factor Analysis
Souzdalnitski D, Bolinske T, Vadivelu N. Pain Quality Assessment Scale: Practical Implications of Factor Analysis. The Clinical Journal Of Pain 2009, 25: 453. PMID: 19454882, DOI: 10.1097/ajp.0b013e318193cf50.Peer-Reviewed Original ResearchThe Urgent Need for Pain Management Training
Vadivelu N, Kombo N, Hines RL. The Urgent Need for Pain Management Training. Academic Medicine 2009, 84: 408. PMID: 19318764, DOI: 10.1097/acm.0b013e31819a8358.Peer-Reviewed Original Research
2008
Management of chronic pain in the elderly: focus on transdermal buprenorphine
Vadivelu N, Hines RL. Management of chronic pain in the elderly: focus on transdermal buprenorphine. Clinical Interventions In Aging 2008, Volume 3: 421-430. PMID: 18982913, PMCID: PMC2682375, DOI: 10.2147/cia.s1880.Peer-Reviewed Original ResearchConceptsChronic painTransdermal buprenorphineSafety profileChronic cancer painChronic nonmalignant painNew treatment optionsRelative safety profileCancer painNonmalignant painRespiratory depressionRenal failureTreatment optionsAnalgesic agentsCeiling doseAnalgesic propertiesPainSide effectsClinical practiceBuprenorphineOlder individualsCeiling effectsMetabolic changesDose dumpingSafe useRecent scientific studies
2007
Buprenorphine: a unique opioid with broad clinical applications.
Vadivelu N, Hines RL. Buprenorphine: a unique opioid with broad clinical applications. Journal Of Opioid Management 2007, 3: 49-58. PMID: 17367094, DOI: 10.5055/jom.2007.0038.Peer-Reviewed Original ResearchConceptsAnti-inflammatory agentsPartial mu agonistRoute of administrationUnique opioidPerioperative painAdequate analgesiaAnalgesic potentialMu agonistsBroad clinical applicationOpioid addictionAddictive potentialClinical applicationBuprenorphineAgonistsPositive resultsAnalgesiaMedicationsOpioidsPainAdministration
2003
Chronic Testicular Pain in a Patient with Diverticulitis
Vadivelu N, Tundis D. Chronic Testicular Pain in a Patient with Diverticulitis. Journal Of Pain And Symptom Management 2003, 25: 404-405. PMID: 12727036, DOI: 10.1016/s0885-3924(03)00100-3.Peer-Reviewed Original Research
2000
Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care
Berger J, Ryan A, Vadivelu N, Merriam P, Rever L, Harrison P. Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care. American Journal Of Hospice And Palliative Medicine® 2000, 17: 127-134. PMID: 11406957, DOI: 10.1177/104990910001700213.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesicsCognition DisordersDrug Therapy, CombinationFemaleFentanylHumansHypnotics and SedativesInfusions, IntravenousKetamineMaleMidazolamMiddle AgedNeoplasmsPainPain MeasurementPsychomotor AgitationReceptors, N-Methyl-D-AspartateRetrospective StudiesTerminal CareTreatment Outcome