Featured Publications
Analysis of Multiple Routes of Analgesic Administration in the Immediate Postoperative Period: a 10-Year Experience
Vadivelu N, Kai AM, Dai F, Dabu-Bondoc S. Analysis of Multiple Routes of Analgesic Administration in the Immediate Postoperative Period: a 10-Year Experience. Current Pain And Headache Reports 2019, 23: 22. PMID: 30854578, DOI: 10.1007/s11916-019-0754-4.Peer-Reviewed Original ResearchConceptsPain scoresAnalgesic administrationPostoperative painPost-anesthesia care unitYale-New Haven HospitalImmediate postoperative painPostoperative pain scoresPurpose of ReviewAnSignificant pain reliefImmediate postoperative periodConsecutive surgical casesTime of dischargeRoute of administrationCommon routeAdverse side effectsNew Haven HospitalIndividual analgesicsNeuraxial routeAnalgesia administrationNeuraxial analgesiaPain reliefPostoperative periodSynergistic analgesiaCare unitParenteral route
2014
Intrathecal drug delivery for chronic pain management-scope, limitations and future
Czernicki M, Sinovich G, Mihaylov I, Nejad B, Kunnumpurath S, Kodumudi G, Vadivelu N. Intrathecal drug delivery for chronic pain management-scope, limitations and future. Journal Of Clinical Monitoring And Computing 2014, 29: 241-249. PMID: 25173564, DOI: 10.1007/s10877-014-9607-1.Peer-Reviewed Original ResearchConceptsIntrathecal drug delivery systemsChronic painOptimal medical managementIntrathecal drug deliveryDifferent implantation techniquesLicensing of drugsSevere morbidityMedical managementMuscle spasmMain indicationsIntrathecal useInvasive techniquesOutcome studiesPainAdverse effectsHealthcare practitionersImplantation techniqueTherapyDrug delivery systemsTherapy systemReview articleDelivery systemDate knowledgeMorbiditySpasm
2011
Peripheral opioid receptor agonists for analgesia: a comprehensive review.
Vadivelu N, Mitra S, Hines RL. Peripheral opioid receptor agonists for analgesia: a comprehensive review. Journal Of Opioid Management 2011, 7: 55-68. PMID: 21434585, DOI: 10.5055/jom.2011.0049.Peer-Reviewed Original ResearchConceptsPeripheral opioid receptorsOpioid receptor agonistsOpioid receptorsReceptor agonistOpioid analgesiaPeripheral opioid receptor agonistDelta-opioid receptor agonistPhase I clinical trialPeripheral opioid agonistPeripheral opioid analgesiaDorsal root gangliaObvious theoretical advantagesOpioid agonist activityPeripheral muAfferent nervesAfferent neuronsOpioid analgesicsPeripheral terminalsCentral actionOpioid agonistsAntidiarrheal drugsOpioidergic systemRoot gangliaClinical trialsPeripheral tissues
2009
Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements
Dabu-Bondoc S, Vadivelu N, Benson J, Perret D, Kain ZN. Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements. Anesthesia & Analgesia 2009, 110: 208-210. PMID: 19861358, DOI: 10.1213/ane.0b013e3181bea424.Peer-Reviewed Original ResearchConceptsPerioperative analgesic requirementsAnalgesic requirementsGeneral anesthesiaTreatment groupsVisual analog scale scoreIntraoperative analgesic requirementsIntraoperative fentanyl consumptionPostoperative pain scoresAnalog scale scoreFentanyl consumptionPain scoresSurgical outpatientsScale scoreControl groupAnesthesiaMusic groupScoresGroupSubjectsVecuroniumOutpatientsLOW‐DOSE KETAMINE AS AN ADJUNCT TO ROUTINE PAIN PRACTICE: ARE WE READY YET?
Souzdalnitski D, Vadivelu N, Chung KS. LOW‐DOSE KETAMINE AS AN ADJUNCT TO ROUTINE PAIN PRACTICE: ARE WE READY YET? Pain Practice 2009, 9: 405-406. PMID: 19740273, DOI: 10.1111/j.1533-2500.2009.00302.x.Peer-Reviewed Original Research
2000
Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care
Berger J, Ryan A, Vadivelu N, Merriam P, Rever L, Harrison P. Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care. American Journal Of Hospice And Palliative Medicine® 2000, 17: 127-134. PMID: 11406957, DOI: 10.1177/104990910001700213.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesicsCognition DisordersDrug Therapy, CombinationFemaleFentanylHumansHypnotics and SedativesInfusions, IntravenousKetamineMaleMidazolamMiddle AgedNeoplasmsPainPain MeasurementPsychomotor AgitationReceptors, N-Methyl-D-AspartateRetrospective StudiesTerminal CareTreatment Outcome