2014
Perioperative dilemma: challenges of the management of a patient on mega doses of morphine and methadone.
Kaye AD, Alian AA, Vadivelu N, Chung KS. Perioperative dilemma: challenges of the management of a patient on mega doses of morphine and methadone. Journal Of Opioid Management 2014, 10: 69-72. PMID: 24604572, DOI: 10.5055/jom.2014.0194.Peer-Reviewed Original ResearchConceptsOpioid-induced hyperalgesiaHigh dosesHigh-dose opioidsCancer-related painPresent case reportMega dosesOpioid requirementsOpioid managementMetastatic leiomyosarcomaAgonist clonidineCase reportPotent analgesicOpioidsPatientsSuccessful managementDosesPainMethadoneMorphineHyperalgesiaClonidineAnalgesicsLeiomyosarcomaManagementAntagonist
2012
Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay
Dabu-Bondoc S, Vadivelu N, Shimono C, English A, Kosarussavadi B, Dai F, Shelley K, Feinleib J. Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay. Anesthesia & Analgesia 2012, 117: 591-596. PMID: 22253268, DOI: 10.1213/ane.0b013e3182458f9e.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAmbulatory Surgical ProceduresAnesthesia, GeneralAntiemeticsCritical CareDouble-Blind MethodFemaleGlucoseGynecologic Surgical ProceduresHumansHysteroscopyInjections, IntravenousIntensive Care UnitsLaparoscopyLength of StayMiddle AgedPostoperative Nausea and VomitingSolutionsTreatment OutcomeYoung AdultConceptsPostanesthesia care unitRinger's lactate solutionDextrose administrationControl groupLactate solutionPostanesthesia care unit lengthDextrose 5Antiemetic rescue medicationIntravenous dextrose administrationPostoperative nausea scoresRate of PONVRescue antiemetic medicationRescue medication requirementsStandardized general anesthesiaPlacebo-controlled trialPostoperative hospital stayASA class ICommon postoperative complicationPONV managementPONV ratePONV scoresRescue medicationUnanticipated admissionAntiemetic medicationHospital stay
2009
Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements
Dabu-Bondoc S, Vadivelu N, Benson J, Perret D, Kain ZN. Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements. Anesthesia & Analgesia 2009, 110: 208-210. PMID: 19861358, DOI: 10.1213/ane.0b013e3181bea424.Peer-Reviewed Original ResearchConceptsPerioperative analgesic requirementsAnalgesic requirementsGeneral anesthesiaTreatment groupsVisual analog scale scoreIntraoperative analgesic requirementsIntraoperative fentanyl consumptionPostoperative pain scoresAnalog scale scoreFentanyl consumptionPain scoresSurgical outpatientsScale scoreControl groupAnesthesiaMusic groupScoresGroupSubjectsVecuroniumOutpatientsPain Quality Assessment Scale: Practical Implications of Factor Analysis
Souzdalnitski D, Bolinske T, Vadivelu N. Pain Quality Assessment Scale: Practical Implications of Factor Analysis. The Clinical Journal Of Pain 2009, 25: 453. PMID: 19454882, DOI: 10.1097/ajp.0b013e318193cf50.Peer-Reviewed Original Research
2008
Management of chronic pain in the elderly: focus on transdermal buprenorphine
Vadivelu N, Hines RL. Management of chronic pain in the elderly: focus on transdermal buprenorphine. Clinical Interventions In Aging 2008, Volume 3: 421-430. PMID: 18982913, PMCID: PMC2682375, DOI: 10.2147/cia.s1880.Peer-Reviewed Original ResearchConceptsChronic painTransdermal buprenorphineSafety profileChronic cancer painChronic nonmalignant painNew treatment optionsRelative safety profileCancer painNonmalignant painRespiratory depressionRenal failureTreatment optionsAnalgesic agentsCeiling doseAnalgesic propertiesPainSide effectsClinical practiceBuprenorphineOlder individualsCeiling effectsMetabolic changesDose dumpingSafe useRecent scientific studies
2000
Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care
Berger J, Ryan A, Vadivelu N, Merriam P, Rever L, Harrison P. Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care. American Journal Of Hospice And Palliative Medicine® 2000, 17: 127-134. PMID: 11406957, DOI: 10.1177/104990910001700213.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesicsCognition DisordersDrug Therapy, CombinationFemaleFentanylHumansHypnotics and SedativesInfusions, IntravenousKetamineMaleMidazolamMiddle AgedNeoplasmsPainPain MeasurementPsychomotor AgitationReceptors, N-Methyl-D-AspartateRetrospective StudiesTerminal CareTreatment Outcome