Featured Publications
ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting
Zwolinski N, Patel K, Vadivelu N, Kodumudi G, Kaye A. ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting. Current Pain And Headache Reports 2023, 27: 65-79. PMID: 37079258, PMCID: PMC10116112, DOI: 10.1007/s11916-023-01108-3.Peer-Reviewed Original ResearchConceptsSubstance use disordersSubstance use disorder patientsAmbulatory patientsUse disordersDisorder patientsERAS protocolPerioperative pain managementAmbulatory surgery settingHospital quality metricsAmbulatory surgical settingAmbulatory surgery casesPerioperative protocolPain managementAdverse outcomesAmbulatory surgeryPharmacodynamic profileSurgery settingAmbulatory proceduresSurgery casesClinical dataEarly recoveryAbused substancesSurgical settingPatientsSubspecialty groupsAmbulatory Pain Management in the Pediatric Patient Population
Oliver JA, Oliver LA, Aggarwal N, Baldev K, Wood M, Makusha L, Vadivelu N, Lichtor L. Ambulatory Pain Management in the Pediatric Patient Population. Current Pain And Headache Reports 2022, 26: 15-23. PMID: 35129824, DOI: 10.1007/s11916-022-00999-y.Peer-Reviewed Original ResearchMeSH KeywordsAmbulatory Surgical ProceduresAnalgesiaAnalgesics, OpioidAnesthesia, ConductionChildHumansPain ManagementPain, PostoperativeConceptsPain managementPostoperative painPediatric ambulatory surgical patientsPostoperative pain controlAmbulatory surgical patientsSevere postoperative painExtent of painPeripheral nerve blocksPediatric ambulatory surgeryPediatric patient populationNon-pharmacological techniquesRandomized control studyEvidence-based approachMultimodal analgesiaPain controlSurgical patientsNerve blockPediatric populationAmbulatory surgeryPatient populationMost centersControl studyPainScientific evidenceMultimodal approachAnalgesia for Gynecologic Oncologic Surgeries: A Narrative Review
Patel K, Shergill S, Vadivelu N, Rajput K. Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review. Current Pain And Headache Reports 2022, 26: 1-13. PMID: 35118596, DOI: 10.1007/s11916-022-00998-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHyperthermic intraperitoneal chemotherapyCytoreductive surgeryPain managementNarrative reviewOptimal perioperative pain managementGynecologic oncologic surgeryPerioperative analgesic planPostoperative pain managementPerioperative pain managementLocal anesthetic infiltrationInvasive cancer surgeryMultimodal analgesicsPreemptive analgesiaMultimodal analgesiaPostoperative painAnalgesic planAnesthetic infiltrationGynecologic malignanciesIntraperitoneal chemotherapyPerioperative periodSurgery protocolThoracic epiduralCancer surgeryChronic painNeuraxial techniquesUltrasound-Guided Neuraxial Anesthesia
Li J, Krishna R, Zhang Y, Lam D, Vadivelu N. Ultrasound-Guided Neuraxial Anesthesia. Current Pain And Headache Reports 2020, 24: 59. PMID: 32812182, DOI: 10.1007/s11916-020-00895-3.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesia, ConductionAnesthesiologyCentral Nervous SystemHumansLumbar VertebraePain ManagementUltrasonographyConceptsNeuraxial anesthesiaHigher first-attempt success rateFirst-attempt success rateNon-obstetric patientsAcute pain managementAttempt success ratePurpose of ReviewTherePain managementRegional anesthesiaNeuraxial spacePatient safety implicationsVertebral levelAnesthesiaOverall efficacyRecent FindingsUltrasoundNeedle passPatient safetyCatheter visualizationUltrasound utilizationClinical accuracySuccess rateCommon typeClinical applicationUltrasoundPatientsAnalysis of Multiple Routes of Analgesic Administration in the Immediate Postoperative Period: a 10-Year Experience
Vadivelu N, Kai AM, Dai F, Dabu-Bondoc S. Analysis of Multiple Routes of Analgesic Administration in the Immediate Postoperative Period: a 10-Year Experience. Current Pain And Headache Reports 2019, 23: 22. PMID: 30854578, DOI: 10.1007/s11916-019-0754-4.Peer-Reviewed Original ResearchConceptsPain scoresAnalgesic administrationPostoperative painPost-anesthesia care unitYale-New Haven HospitalImmediate postoperative painPostoperative pain scoresPurpose of ReviewAnSignificant pain reliefImmediate postoperative periodConsecutive surgical casesTime of dischargeRoute of administrationCommon routeAdverse side effectsNew Haven HospitalIndividual analgesicsNeuraxial routeAnalgesia administrationNeuraxial analgesiaPain reliefPostoperative periodSynergistic analgesiaCare unitParenteral route
2016
Role of Alternative Therapies for Chronic Pain Syndromes
Thomas DA, Maslin B, Legler A, Springer E, Asgerally A, Vadivelu N. Role of Alternative Therapies for Chronic Pain Syndromes. Current Pain And Headache Reports 2016, 20: 29. PMID: 27038968, DOI: 10.1007/s11916-016-0562-z.Peer-Reviewed Original ResearchMeSH KeywordsAcupuncture TherapyBiofeedback, PsychologyChronic PainComplementary TherapiesHumansNeck PainPain ManagementConceptsChronic painWhole-body cryotherapyExercise therapyPain statesAlternative therapiesComplimentary therapiesLong-term pain statesChronic pain syndromePhysical exercise therapyTreatment of headacheCognitive behavior therapyNeck painPain syndromeAlternate therapyBiofeedback therapyPain psychologySham controlsPainHerbal supplementsAlternative medicineTherapyBiopsychosocial approachBehavior therapyBiopsychosocial modelNew modalityFacial Pain Update: Advances in Neurostimulation for the Treatment of Facial Pain
Maniam R, Kaye AD, Vadivelu N, Urman RD. Facial Pain Update: Advances in Neurostimulation for the Treatment of Facial Pain. Current Pain And Headache Reports 2016, 20: 24. PMID: 26896948, DOI: 10.1007/s11916-016-0553-0.Peer-Reviewed Original ResearchConceptsInterventional pain proceduresCraniofacial painFacial painPharmacological therapyPain proceduresHigh-frequency spinal cord stimulationPersistent idiopathic facial painPeripheral nerve field stimulationIdiopathic facial painInterventional pain techniquesSphenopalatine ganglion stimulationTrigeminal neuropathic painTraditional pharmacological therapyInterventional pain therapySmall patient cohortSpinal cord stimulationDeep brain stimulationInvasive implantation techniquesGanglion stimulationNeuropathic painPain statesPain therapyTrigeminal neuralgiaCord stimulationPatient cohort
2013
Clinical applications of oxymorphone.
Vadivelu N, Maria M, Jolly S, Rosenbloom J, Prasad A, Kaye AD. Clinical applications of oxymorphone. Journal Of Opioid Management 2013, 9: 439-52. PMID: 24481932, DOI: 10.5055/jom.2013.0186.Peer-Reviewed Original ResearchConceptsNew oral preparationNew oral formulationSemisynthetic opioid analgesicSpecific side effectsSevere painOpioid analgesicsParenteral formClinical indicationsOral preparationsStudy populationPharmacological considerationsOral formulationSide effectsPatient needsUS FoodDrug AdministrationHealthcare providersParenteral formulationsClinical applicationPainImportant drugsOxymorphoneAdditional optionPyridomorphinansSpecific considerationsCommon misconceptions about opioid use for pain management at the end of life.
Berger JM, Vadivelu N. Common misconceptions about opioid use for pain management at the end of life. The AMA Journal Of Ethic 2013, 15: 403-9. PMID: 23680560, DOI: 10.1001/virtualmentor.2013.15.5.ecas1-1305.Peer-Reviewed Original Research
2012
Acute Pain in Undergraduate Medical Education: An Unfinished Chapter!
Vadivelu N, Mitra S, Hines R, Elia M, Rosenquist RW. Acute Pain in Undergraduate Medical Education: An Unfinished Chapter! Pain Practice 2012, 12: 663-671. PMID: 22712557, DOI: 10.1111/j.1533-2500.2012.00580.x.Peer-Reviewed Original ResearchConceptsUndergraduate medical educationMedical school curriculumAcute pain diagnosisSchool curriculumEducational institutionsAcute painSignificant patient sufferingMedical educationMedical schoolsAdequate instructionHealth educatorsEducationPain educationCompassionate approachAcute pain syndromePain management specialistsRisk of chronicityAcute pain managementUnfinished chapterGlobal healthcare problemPain syndromeHealthcare imperativePain managementPain diagnosisIntegral part
2011
Pain Relief in Laparoscopic Cholecystectomy—A Review of the Current Options
Mitra S, Khandelwal P, Roberts K, Kumar S, Vadivelu N. Pain Relief in Laparoscopic Cholecystectomy—A Review of the Current Options. Pain Practice 2011, 12: 485-496. PMID: 22008277, DOI: 10.1111/j.1533-2500.2011.00513.x.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsLocal anestheticsLaparoscopic cholecystectomyPain reliefTransversus abdominis plane blockCardiovascular adverse effectsPort-site infiltrationIntra-operative periodSingle modality interventionsFavorable pharmacological characteristicsAnti-inflammatory drugsCOX-2 inhibitorsCyclooxygenase-2 inhibitorNSAID/COXTAP blockNoncardiac surgeryPlane blockSafe analgesiaEarly instillationIntraperitoneal instillationPharmacological characteristicsFibrin sealantInstillationCurrent optionsAdverse effects