Recent advances in elucidating pain mechanisms
Vadivelu N, Sinatra R. Recent advances in elucidating pain mechanisms. Current Opinion In Anaesthesiology 2005, 18: 540. PMID: 16534290, DOI: 10.1097/01.aco.0000183109.27297.75.Peer-Reviewed Original ResearchCentral sensitizationPain mechanismsChronic painN-methyl-D-asparate antagonistNon-opioid medicationsSpinal cord hyperexcitabilityCyclooxygenase-2 inhibitorNew synaptic connectionsSecondary hyperalgesiaOpioid medicationsPain controlPain syndromeNerve injuryPain modulationPain statesNociceptor sensitizationNeural injuryNew opioidSecond messenger systemsNervous systemAcute tissueSynaptic connectionsReceptor systemMessenger systemsSensitization