2024
The diagnostic value of the central vein sign in radiologically isolated syndrome
Landes‐Chateau C, Levraut M, Okuda D, Themelin A, Cohen M, Kantarci O, Siva A, Pelletier D, Mondot L, Lebrun‐Frenay C, Lebrun‐Frenay C, Kantarci O, Siva A, Pelletier D, Azevedo C, Makhani N, Okuda D. The diagnostic value of the central vein sign in radiologically isolated syndrome. Annals Of Clinical And Translational Neurology 2024, 11: 662-672. PMID: 38186317, PMCID: PMC10963291, DOI: 10.1002/acn3.51986.Peer-Reviewed Original ResearchConceptsRadiologically isolated syndromeCentral vein signCVS+ lesionsNon-MSMultiple sclerosisControl group of sex-RIS diagnosisAge-matched subjectsDetectable preclinical phaseProportion of lesionsWhite matter lesionsGroup of sex-Effective imaging biomarkerMagnetic resonance imagingDiagnostic performanceDiagnostic accuracyDiagnostic valueLesion criteriaImaging biomarkersLesionsResonance imagingLesion-specificAbsolute numberControl groupROC comparisons
2017
Abnormal Fluid-Attenuated Inversion Recovery Signal in the Internal Capsule: A Novel Brain Magnetic Resonance Imaging Finding in a Child With Acute Flaccid Myelitis
Makhani N, Mahajan A. Abnormal Fluid-Attenuated Inversion Recovery Signal in the Internal Capsule: A Novel Brain Magnetic Resonance Imaging Finding in a Child With Acute Flaccid Myelitis. Pediatric Neurology 2017, 73: 108-109. PMID: 28262551, DOI: 10.1016/j.pediatrneurol.2017.01.031.Peer-Reviewed Original Research
2016
Oral Dimethyl Fumarate in Children With Multiple Sclerosis: A Dual-Center Study
Makhani N, Schreiner T. Oral Dimethyl Fumarate in Children With Multiple Sclerosis: A Dual-Center Study. Pediatric Neurology 2016, 57: 101-104. PMID: 26996405, DOI: 10.1016/j.pediatrneurol.2016.01.010.Peer-Reviewed Original ResearchConceptsOral dimethyl fumarateMultiple sclerosisDimethyl fumarateSide effectsFirst-line injectable therapiesBrain magnetic resonance imagingAbnormal liver transaminasesDual-Center ExperienceUsual adult doseMonths of therapyNew T2 lesionsFirst-line therapyCommon side effectsMagnetic resonance imaging (MRI) parametersPediatric multiple sclerosisDual-center studyChildren 18 yearsFormal clinical trialsMagnetic resonance imagingLiver transaminasesDisability scoresLaboratory abnormalitiesOral medicationsRelapse rateRetrospective review