2023
The radiologically isolated syndrome: revised diagnostic criteria
Lebrun-Frénay C, Okuda D, Siva A, Landes-Chateau C, Azevedo C, Mondot L, Carra-Dallière C, Zephir H, Louapre C, Durand-Dubief F, Le Page E, Bensa C, Ruet A, Ciron J, Laplaud D, Casez O, Mathey G, de Seze J, Zeydan B, Makhani N, Tutuncu M, Levraut M, Cohen M, Thouvenot E, Pelletier D, Kantarci O. The radiologically isolated syndrome: revised diagnostic criteria. Brain 2023, 146: 3431-3443. PMID: 36864688, PMCID: PMC11004931, DOI: 10.1093/brain/awad073.Peer-Reviewed Original ResearchConceptsRadiologically isolated syndromeClinical eventsGroup 1Risk factorsDIS criteriaPresence of spinal cord lesionsClinical follow-up timeCSF-restricted oligoclonal bandsMultivariate Cox regression modelDiagnostic criteriaFocal T2 hyperintensitiesGadolinium-enhancing lesionsMultiple sclerosisNegative predictive valueFollow-up scansFollow-up timeArea under the curveClass I evidenceSpinal cord lesionsCox regression modelsRisk of developmentWhite matter lesionsProspective databaseSymptomatic MST2 lesions
2019
Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome
Makhani N, Lebrun C, Siva A, Narula S, Wassmer E, Brassat D, Brenton JN, Cabre P, Carra Dallière C, de Seze J, Durand Dubief F, Inglese M, Langille M, Mathey G, Neuteboom RF, Pelletier J, Pohl D, Reich DS, Ignacio Rojas J, Shabanova V, Shapiro ED, Stone RT, Tenembaum S, Tintoré M, Uygunoglu U, Vargas W, Venkateswaren S, Vermersch P, Kantarci O, Okuda DT, Pelletier D, . Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome. Multiple Sclerosis Journal - Experimental Translational And Clinical 2019, 5: 2055217319836664. PMID: 30915227, PMCID: PMC6429663, DOI: 10.1177/2055217319836664.Peer-Reviewed Original ResearchOligoclonal bandsMultiple sclerosisCerebrospinal fluidDiagnostic criteriaCentral nervous system demyelinationMagnetic resonance imaging criteriaFirst clinical eventCerebrospinal fluid analysisNervous system demyelinationOptimal diagnostic criteriaDiagnostic indexMagnetic resonanceSpecificity 72.7Historical cohortProspective studyClinical eventsMRI criteriaSensitivity 66.7Imaging criteriaDiagnostic certaintySpecificity 83.3SyndromeFluid analysisSensitivity 76.5Demyelination
2013
Incidence and prevalence of multiple sclerosis in Europe: a systematic review
Kingwell E, Marriott JJ, Jetté N, Pringsheim T, Makhani N, Morrow SA, Fisk JD, Evans C, Béland SG, Kulaga S, Dykeman J, Wolfson C, Koch MW, Marrie RA. Incidence and prevalence of multiple sclerosis in Europe: a systematic review. BMC Neurology 2013, 13: 128. PMID: 24070256, PMCID: PMC3856596, DOI: 10.1186/1471-2377-13-128.Peer-Reviewed Original ResearchConceptsCurrent diagnostic criteriaIncidence estimatesDiagnostic criteriaOriginal population-based studiesEpidemiology of MSPrevalence of MSPopulation-based studyPeer-reviewed full-text articlesComprehensive literature searchFull-text articlesBackgroundMultiple sclerosisMS incidenceMS prevalenceNeurological disabilityMultiple sclerosisCase definitionCommon causeInclusion criteriaMethodological qualityEpidemiological dataRecent studiesSystematic reviewPrevalenceLiterature searchIncidence