2017
AP2 α modulates cystic fibrosis transmembrane conductance regulator function in the human intestine
Kumari V, Desai S, Ameen NA. AP2 α modulates cystic fibrosis transmembrane conductance regulator function in the human intestine. Journal Of Cystic Fibrosis 2017, 16: 327-334. PMID: 28438500, PMCID: PMC5502754, DOI: 10.1016/j.jcf.2017.03.012.Peer-Reviewed Original Research
2013
Regulated traffic of anion transporters in mammalian Brunner's glands: a role for water and fluid transport
Collaco AM, Jakab RL, Hoekstra NE, Mitchell KA, Brooks A, Ameen NA. Regulated traffic of anion transporters in mammalian Brunner's glands: a role for water and fluid transport. AJP Gastrointestinal And Liver Physiology 2013, 305: g258-g275. PMID: 23744739, PMCID: PMC3742856, DOI: 10.1152/ajpgi.00485.2012.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnion Transport ProteinsAquaporin 5BicarbonatesBiological TransportBrunner GlandsCarbacholCeliac DiseaseChloridesCyclic AMPCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDuodenumHumansMaleProtonsRatsRats, Sprague-DawleySecond Messenger SystemsVacuolar Proton-Translocating ATPasesWaterConceptsCystic fibrosis transmembrane conductance regulatorV-ATPaseProton-pumping vacuolar ATPaseApical membraneDistinct membrane domainsFibrosis transmembrane conductance regulatorRat Brunner's glandsTransmembrane conductance regulatorSodium bicarbonate cotransporterAnion transportersApical traffickingMembrane domainsChloride cotransporter 1Secretion of glycoproteinsVacuolar ATPaseSecond messenger activationTransporter localizationConductance regulatorSubcellular distributionAquaporin 5 water channelFunctional transportPKA inhibitorAntimicrobial peptidesTransportersBasolateral membrane
1996
A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature-sensitive processing defect in vivo.
French PJ, van Doorninck JH, Peters RH, Verbeek E, Ameen NA, Marino CR, de Jonge HR, Bijman J, Scholte BJ. A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature-sensitive processing defect in vivo. Journal Of Clinical Investigation 1996, 98: 1304-1312. PMID: 8823295, PMCID: PMC507556, DOI: 10.1172/jci118917.Peer-Reviewed Original Research
1995
A unique subset of rat and human intestinal villus cells express the cystic fibrosis transmembrane conductance regulator
Ameen N, Ardito T, Kashgarian M, Marino C. A unique subset of rat and human intestinal villus cells express the cystic fibrosis transmembrane conductance regulator. Gastroenterology 1995, 108: 1016-1023. PMID: 7535272, DOI: 10.1016/0016-5085(95)90198-1.Peer-Reviewed Original ResearchConceptsProximal small intestineCrypt epithelial cellsVillus cellsSmall intestineHuman proximal small intestineCystic fibrosis transmembrane conductance regulatorEpithelial cellsSurface marker expressionFibrosis transmembrane conductance regulatorBrush border sucraseTransmembrane conductance regulatorIntestinal villus cellsBACKGROUND/Marker antibodiesMarker expressionUnique subsetVillus enterocytesConductance regulatorIntestineLactase expressionBrush border