Characterization of CFTR High Expresser cells in the intestine
Jakab RL, Collaco AM, Ameen NA. Characterization of CFTR High Expresser cells in the intestine. AJP Gastrointestinal And Liver Physiology 2013, 305: g453-g465. PMID: 23868408, PMCID: PMC3761243, DOI: 10.1152/ajpgi.00094.2013.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAlkaline PhosphataseAnimalsCyclic AMPCystic Fibrosis Transmembrane Conductance RegulatorIntestinal MucosaIntestine, SmallMaleMicrovilliProtein TransportQa-SNARE ProteinsRatsRats, Sprague-DawleySodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersSodium-Potassium-Exchanging ATPaseSolute Carrier Family 12, Member 2ConceptsCHE cellsNeighboring enterocytesVacuolar ATPase proton pumpCystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channelDouble-label immunofluorescence microscopyEightfold higher levelsBrush border membraneRegulatory factors NHERF1Crypt-villus axisCFTR abundanceSyntaxin 3Myosin-1aApical domain