2020
Secretory Diarrhea
Ameen N, Kopic S, Ahsan K, Figueroa-Hall L. Secretory Diarrhea. Physiology In Health And Disease 2020, 41-76. DOI: 10.1007/978-3-030-55310-4_2.Peer-Reviewed Original Research
2018
Establishment of Microvillus Inclusion Disease (MVID) human models using small intestinal enteroids and embryonic stem cells
Figueroa‐Hall L, Ameen N. Establishment of Microvillus Inclusion Disease (MVID) human models using small intestinal enteroids and embryonic stem cells. The FASEB Journal 2018, 32: 750.31-750.31. DOI: 10.1096/fasebj.2018.32.1_supplement.750.31.Peer-Reviewed Original ResearchMicrovillus inclusion diseaseHuman intestinal modelSmall intestineIntestinal modelSeverity of illnessIntestinal organoidsSmall intestinal modelProximal small intestineCancer-derived cell linesFull-text articlesDevelopment of therapiesStem cellsIntestinal cell modelSmall intestinal organoidsIntestinal enteroidsInclusion diseasePathognomonic featuresSecretory diarrheaEpithelial diseaseHuman embryonic stem cellsIntestinal tissueIntestine resultsTransporter traffickingAppropriate research modelsLentiviral transfection
2016
Identification of intestinal ion transport defects in microvillus inclusion disease
Kravtsov DV, Ahsan MK, Kumari V, van Ijzendoorn SC, Reyes-Mugica M, Kumar A, Gujral T, Dudeja PK, Ameen NA. Identification of intestinal ion transport defects in microvillus inclusion disease. AJP Gastrointestinal And Liver Physiology 2016, 311: g142-g155. PMID: 27229121, PMCID: PMC4967175, DOI: 10.1152/ajpgi.00041.2016.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingCaco-2 CellsChloride-Bicarbonate AntiportersCystic Fibrosis Transmembrane Conductance RegulatorEnterocytesGene Expression RegulationHumansIon TransportJejunumMalabsorption SyndromesMembrane Transport ProteinsMicrovilliMucolipidosesMyosin Heavy ChainsMyosin Type VPhenotypePhosphoproteinsRNA InterferenceSignal TransductionSodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersSulfate TransportersTranscription FactorsTransfectionYAP-Signaling ProteinsConceptsMicrovillus inclusion diseaseStool lossVillus atrophyInclusion diseaseEnterocyte maturationMicrovillus inclusionsIntestinal fluid transportIntestinal cell modelIon transport defectImmunohistochemical stainingSecretory diarrheaBrush border defectsImmature enterocytesC2BBe cellsT84 cellsElectrophysiological approachesCFTR ion transportBB membraneLoss of MYO5BEnterocytesFunctional CFTRDiarrheaAtrophyFunction mutationsCFTR localization
2015
Secretory Diarrhea
Ameen N, Kopic S, Ahsan M, Kravtsov D. Secretory Diarrhea. Physiology In Health And Disease 2015, 957-990. DOI: 10.1007/978-1-4939-3366-2_29.Peer-Reviewed Original Research