2015
Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI
Hegan PS, Kravtsov DV, Caputo C, Egan ME, Ameen NA, Mooseker MS. Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI. Cytoskeleton 2015, 72: 455-476. PMID: 26286357, PMCID: PMC4715533, DOI: 10.1002/cm.21238.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsApoptosisCell MembraneCell NucleusColitisCrosses, GeneticCystic Fibrosis Transmembrane Conductance RegulatorCytoskeletonDisease ProgressionDuodenumEndosomesEpitheliumGenotypeIn Situ Nick-End LabelingIntestinal MucosaIntestinesMaleMiceMice, KnockoutMicroscopy, Electron, TransmissionMicroscopy, FluorescenceMicrovilliMutationMyosin Heavy ChainsMyosin Type IPhosphates
2001
Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia
Ameen N, Figueroa Y, Salas P. Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia. Journal Of Cell Science 2001, 114: 563-575. PMID: 11171325, DOI: 10.1242/jcs.114.3.563.Peer-Reviewed Original ResearchConceptsIntermediate filamentsPolarized epithelial cellsApical membrane proteinsEpithelial cellsSyntaxin 3Apical domainFemale sterilityMembrane proteinsApical markerNovel functionGamma-tubulinNovel roleApical poleSimple epitheliaCell typesColorectal hyperplasiaCK intermediate filamentsNull micePhenotypeBasolateral levelsNecrotic cellsMembrane phenotypeCellsFilamentsCytoplasm of enterocytes