2022
Elevated 5‐hydroxytryptamine in COVID‐19 Stimulates ANO1 Mediated Cl Secretion in Lung & Intestinal Epithelial Cells
Hoque K, Hayashi M, Sheikh I, Banerjee A, Verma S, Leblanc N, Zeiss C, Ameen N, Chakraborty S. Elevated 5‐hydroxytryptamine in COVID‐19 Stimulates ANO1 Mediated Cl Secretion in Lung & Intestinal Epithelial Cells. The FASEB Journal 2022, 36: 10.1096/fasebj.2022.36.s1.0r556. PMCID: PMC9348250, DOI: 10.1096/fasebj.2022.36.s1.0r556.Peer-Reviewed Original ResearchEnterochromaffin cell hyperplasiaCalu-3 cellsSARS-CoV2 infectionCl(-) secretionIntestinal epitheliumCell hyperplasiaColonic tissueCalcium-activated Cl- currentsCOVID-19-associated diarrheaCalcium-activated chloride currentsHuman colorectal cancer tissuesANO1 protein expressionCOVID-19 therapyIntestinal Cl(-) secretionColorectal cancer tissuesUssing chamber experimentsANO1 currentsSeverity of symptomsCOVID-19Human terminal ileumHuman intestinal epitheliumIntestinal epithelial cellsWhole-cell currentsHuman colonic tissueCaco-2 cells
2015
Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI
Hegan PS, Kravtsov DV, Caputo C, Egan ME, Ameen NA, Mooseker MS. Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI. Cytoskeleton 2015, 72: 455-476. PMID: 26286357, PMCID: PMC4715533, DOI: 10.1002/cm.21238.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsApoptosisCell MembraneCell NucleusColitisCrosses, GeneticCystic Fibrosis Transmembrane Conductance RegulatorCytoskeletonDisease ProgressionDuodenumEndosomesEpitheliumGenotypeIn Situ Nick-End LabelingIntestinal MucosaIntestinesMaleMiceMice, KnockoutMicroscopy, Electron, TransmissionMicroscopy, FluorescenceMicrovilliMutationMyosin Heavy ChainsMyosin Type IPhosphatesConceptsActin coreMyosin VIIntestinal epithelial cellsMutant miceMyosin IAMembrane traffickingActin cytoskeletonBB membraneMembrane proteins
2010
T1837 The Vacuolar ATPase Associates With CFTR in Apical Endocytic and Recycling Vesicles and Undergoes cAMP Regulated Trafficking in Intestinal Epithelial Cells
Collaco A, Jakab R, Gorelick F, Ameen N. T1837 The Vacuolar ATPase Associates With CFTR in Apical Endocytic and Recycling Vesicles and Undergoes cAMP Regulated Trafficking in Intestinal Epithelial Cells. Gastroenterology 2010, 138: s-589. DOI: 10.1016/s0016-5085(10)62715-1.Peer-Reviewed Original ResearchRecycling vesiclesIntestinal epithelial cellsEpithelial cellsEndocyticTraffickingCFTRVesiclesAssociatesCellsCAMP