Central Challenges Facing the National Clinical Research Enterprise
Sung NS, Crowley WF, Genel M, Salber P, Sandy L, Sherwood LM, Johnson SB, Catanese V, Tilson H, Getz K, Larson EL, Scheinberg D, Reece EA, Slavkin H, Dobs A, Grebb J, Martinez RA, Korn A, Rimoin D. Central Challenges Facing the National Clinical Research Enterprise. JAMA 2003, 289: 1278-1287. PMID: 12633190, DOI: 10.1001/jama.289.10.1278.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchClinical Trials as TopicConfidentialityConflict of InterestConsensusCooperative BehaviorEvidence-Based MedicineHealth OccupationsHealth PolicyHealth PrioritiesHumansInformation SystemsInformed ConsentInvestmentsNational Academies of Science, Engineering, and Medicine, U.S., Health and Medicine DivisionPatient SelectionPolicy MakingPrivate SectorResearch PersonnelResearch Support as TopicUnited StatesUnited States Government AgenciesConceptsClinical research enterpriseClinical studiesClinical researchPublic health policy makersInstitute of MedicineHealth policy makersSystems of careEntire health care systemBasic science discoveriesHealth care systemResearch RoundtableTranslational blockCare systemHealth decisionsMedical practiceQualified investigatorsScience discoveriesLack of fundingWilling participantsWorkforce trainingResearch enterprise