Noninvasive amino acid turnover predicts human embryo aneuploidy
Olcay IO, Akcay B, Bahceci M, Arici A, Boynukalin K, Yakicier C, Ozpinar A, Basar M. Noninvasive amino acid turnover predicts human embryo aneuploidy. Gynecological Endocrinology 2022, 38: 461-466. PMID: 35481385, DOI: 10.1080/09513590.2022.2068520.Peer-Reviewed Original ResearchConceptsEuploid groupAneuploid groupAmino acid turnoverAneuploid embryosHigher implantation rateAmino acid metabolism profilePotential diagnostic testPreimplantation genetic testingAcid turnoverBlank control groupEmbryo selection criteriaAssisted reproduction technologyMultiple pregnanciesImplantation ratePatient groupAmino acid concentrationsAneuploid blastocystsEmbryo aneuploidyControl groupDay 5IVF clinicsLow success rateGenetic testingCulture mediumTE biopsy