The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats
Ertürküner S, Başar M, Tunçdemir M, Seçkin İ. The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats. Pharmacological Reports 2014, 66: 279-287. PMID: 24911082, DOI: 10.1016/j.pharep.2013.09.010.Peer-Reviewed Original ResearchConceptsUntreated diabetic groupDiabetic groupMesangial matrixControl groupDiabetic nephropathyDiabetes mellitusEnd-stage kidney failureOxidative stressExperimental diabetic nephropathyHigh blood pressureAdult Wistar AlbinoGlomerular mesangial matrixBlood glucose valuesExcessive reactive oxygen species (ROS) productionReactive oxygen species productionBlood pressureKidney weightDiabetic ratsKidney failureImmunohistochemical stainingOxygen species productionPodocyte damageBody weightEnzyme inhibitorsWistar albino