2024
Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk
Brandhorst S, Levine M, Wei M, Shelehchi M, Morgan T, Nayak K, Dorff T, Hong K, Crimmins E, Cohen P, Longo V. Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk. Nature Communications 2024, 15: 1309. PMID: 38378685, PMCID: PMC10879164, DOI: 10.1038/s41467-024-45260-9.Peer-Reviewed Original ResearchConceptsMultiple cardiometabolic risk factorsAssociated with reduced insulin resistanceCardiometabolic risk factorsFasting-mimicking dietImmune system agingRandomized clinical trialsAnalysis of blood samplesAutoimmune cellsBiological ageClinical trialsReduce inflammationMarker changesRisk factorsHepatic fatInsulin resistanceAdult study participantsBlood samplesNormal cellsWeight lossReducing biological ageBiomarker of biological agingDamaged cellsStudy participantsDisease riskAge
2012
Be Well
Kogan AC, Gonzalez J, Hart B, Halloran S, Thomason B, Levine M, Enguidanos S. Be Well. Journal Of Applied Gerontology 2012, 32: 889-901. PMID: 25474803, PMCID: PMC5923899, DOI: 10.1177/0733464812440043.Peer-Reviewed Original ResearchConceptsCommunity-based senior centersMore emergency department visitsOlder adultsCommunity-dwelling older adultsEmergency department visitsLow-impact exerciseMultiple chronic conditionsNutritional education interventionDepartment visitsHospital admissionNutritional counselingChronic conditionsWeekly exerciseWeight managementCohort designPhysical activityHigh riskEducation interventionWeight lossGood nutritionFitness programPerson interviewsSenior centersDepressionFitness tests