Biological Age, Not Chronological Age, Is Associated with Late-Life Depression
Brown PJ, Wall MM, Chen C, Levine ME, Yaffe K, Roose SP, Rutherford BR. Biological Age, Not Chronological Age, Is Associated with Late-Life Depression. The Journals Of Gerontology Series A 2017, 73: 1370-1376. PMID: 28958059, PMCID: PMC6132120, DOI: 10.1093/gerona/glx162.Peer-Reviewed Original ResearchConceptsLate-life depressionCES-D scoresDepressive symptomsBaseline CES-D scoreBiological ageChronological ageCovariate-adjusted regression modelsOlder biological ageEpidemiologic Studies Depression ScaleSignificant depressive symptomsBody Composition StudyMean chronological ageAge-associated changesNumerous physiological systemsAge-related processesKidney functioningLife depressionDepression ScaleDepression groupBrain disordersHealth AgingLongitudinal associationsSymptomsAgeRegression models