2024
Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes
Son M, Riley L, Staniczenko A, Cron J, Yen S, Thomas C, Sholle E, Osborne L, Lipkind H. Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes. JAMA Network Open 2024, 7: e2419268. PMID: 38976271, PMCID: PMC11231799, DOI: 10.1001/jamanetworkopen.2024.19268.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusNeonatal intensive care unitPreterm birthWeeks gestationRisk of HDPPerinatal outcomesLogistic regression modelsIncreased riskPregnant individualsPrenatal vaccinationSmall-for-gestational age birth weightNeonatal intensive care unit admissionCohort studyIncreased risk of PTBOdds ratioIncreased risk of HDPRisk of preterm birthRespiratory syncytial virus seasonRespiratory syncytial virus vaccineRetrospective observational cohort studyNeonatal respiratory distressVaccination statusMultivariate logistic regression modelObservational cohort studyCox regression models
2023
Fetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use?
Leon-Martinez D, Lundsberg L, Culhane J, Zhang J, Son M, Reddy U. Fetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use? American Journal Of Obstetrics And Gynecology 2023, 229: 678.e1-678.e16. PMID: 37348779, DOI: 10.1016/j.ajog.2023.06.035.Peer-Reviewed Original ResearchConceptsNeonatal composite outcomeComposite outcomeFetal growth restrictionGestational ageFetal weightWeeks of gestationPositive likelihood ratioGrowth restrictionNonanomalous singleton pregnanciesPoor neonatal outcomeRetrospective cohort studySingle academic centerWeeks of deliveryDays of deliveryFetal growth referencesElectronic medical recordsProportion of fetusesLikelihood ratioNeonatal morbidityNeonatal outcomesPerinatal outcomesCohort studySingleton pregnanciesNeonatal dataMedical recordsLow-Dose Aspirin during Pregnancy and Postpartum Bleeding
White K, Son M, Lundsberg L, Culhane J, Partridge C, Reddy U, Merriam A. Low-Dose Aspirin during Pregnancy and Postpartum Bleeding. American Journal Of Perinatology 2023, 40: 1390-1397. PMID: 37211010, DOI: 10.1055/a-2096-5199.Peer-Reviewed Original ResearchConceptsLow-dose aspirinPostpartum blood lossTiming of discontinuationBlood lossPostpartum bleedingPostpartum hemorrhageLDA useUse of LDARed blood cell transfusionBlood cell transfusionRetrospective cohort studySystemic lupus erythematosusTime of deliveryDiagnosis of diabetesLogistic regression modelingElectronic medical recordsAspirin 81Ideal dosingPreeclampsia preventionCell transfusionDose aspirinCohort studyHypertensive diseaseLupus erythematosusPrimary outcomeIntravenous iron for treatment of iron deficiency anemia during pregnancy and associated maternal outcomes
Burn M, Lundsberg L, Culhane J, Partridge C, Son M. Intravenous iron for treatment of iron deficiency anemia during pregnancy and associated maternal outcomes. The Journal Of Maternal-Fetal & Neonatal Medicine 2023, 36: 2192855. PMID: 36958808, DOI: 10.1080/14767058.2023.2192855.Peer-Reviewed Original ResearchConceptsIron deficiency anemiaMaternal morbidity compositeIntravenous ironMorbidity compositePotential confoundersElectronic medical recordsPregnant patientsTreatment courseDeficiency anemiaHigh-risk baseline characteristicsMultivariable logistic regression modellingRetrospective cohort studyFull treatment courseHospital electronic medical recordsIntensive care unitLogistic regression modellingGreater increaseMaternal morbidityMaternal outcomesNeonatal outcomesBaseline characteristicsCohort studyBlood transfusionPrimary outcomeTerm delivery
2022
Changes in prenatal testing during the COVID-19 pandemic
Handley S, Ledyard R, Lundsberg L, Passarella M, Yang N, Son M, McKenney K, Greenspan J, Dysart K, Culhane J, Burris H. Changes in prenatal testing during the COVID-19 pandemic. Frontiers In Pediatrics 2022, 10: 1064039. PMID: 36440341, PMCID: PMC9682111, DOI: 10.3389/fped.2022.1064039.Peer-Reviewed Original ResearchProportion of patientsPregnant patientsWeeks' gestationFirst trimesterRetrospective observational cohort studyEarly COVID-19 pandemic periodCOVID-19 pandemicRoutine prenatal testingObservational cohort studyPrenatal testingElectronic health record dataCoronavirus disease 2019 (COVID-19) pandemicAcademic health systemHealth record dataDisease 2019 pandemicMultivariable adjustmentCohort studyPrimary outcomeGestational agePrenatal careAnatomy surveyClaims dataDiabetes testingPatientsCare deliveryOutpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergyPostpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic
Handley SC, Gallagher K, Lindgren E, Lo JY, Burris HH, Dysart KC, Greenspan J, Culhane JF, Son M. Postpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic. Obstetrics And Gynecology 2022, 139: 381-390. PMID: 35115443, DOI: 10.1097/aog.0000000000004687.Peer-Reviewed Original ResearchConceptsCoronavirus disease 2019 (COVID-19) pandemicObstetric patientsHospital readmissionMode of deliveryPostpartum hospitalizationDisease 2019 pandemicHospitalization dischargeCOVID-19 pandemicRetrospective cohort studyWeeks of gestationDays of deliveryLogistic mixed-effects modelsCohort studyHospitalization lengthSecondary outcomesPrimary outcomeAdjusted analysisStudy cohortVaginal birthCesarean birthReadmissionPostpartum lengthPatientsHospitalizationMixed-effects models
2021
Birth Hospital Length of Stay and Rehospitalization During COVID-19
Handley SC, Gallagher K, Breden A, Lindgren E, Lo JY, Son M, Murosko D, Dysart K, Lorch SA, Greenspan J, Culhane JF, Burris HH. Birth Hospital Length of Stay and Rehospitalization During COVID-19. Pediatrics 2021, 149: e2021053498. PMID: 34889449, PMCID: PMC9645693, DOI: 10.1542/peds.2021-053498.Peer-Reviewed Original ResearchConceptsInfant rehospitalizationAdjusted odds ratioTerm infantsBirth hospitalization dischargeBirth hospitalization lengthHealthy term infantsRetrospective cohort studyCoronavirus disease 2019 eraDay of birthCOVID-19Hospitalization dischargePrepandemic eraHospital lengthMultivariable adjustmentCohort studyHospitalization lengthShorter LOSAdjusted analysisOdds ratioRehospitalizationInfantsHealth systemAdditional outcomesCOVID-19 eraMixed effects modelsCoronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population
Son M, Gallagher K, Lo JY, Lindgren E, Burris HH, Dysart K, Greenspan J, Culhane JF, Handley SC. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population. Obstetrics And Gynecology 2021, 138: 542-551. PMID: 34433180, PMCID: PMC8454282, DOI: 10.1097/aog.0000000000004547.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionAdverse pregnancy-related outcomesPregnancy-related outcomesCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicPregnancy outcomesGestational ageSARS-CoV-2 testingDiverse U.S. cohortAdverse pregnancy outcomesRetrospective cohort studyPositive test resultsSARS-CoV-2 diagnosisSignificant differencesNegative test resultsHypertensive disordersPlacental abruptionBaseline characteristicsCohort studyPreterm birthPostpartum hemorrhagePregnant womenCesarean birthU.S. cohortPublic insurance
2018
Maternal Obstetric Complication Rates Remain High in Illinois: A Retrospective Study, 2010–2015
Roy A, Peaceman A, Son M, Feinglass J. Maternal Obstetric Complication Rates Remain High in Illinois: A Retrospective Study, 2010–2015. The Joint Commission Journal On Quality And Patient Safety 2018, 45: 24-30. PMID: 30121161, DOI: 10.1016/j.jcjq.2018.02.007.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityMaternal complicationsCesarean deliveryDelivery complicationsComplication rateSevere maternal morbidity ratesStudy periodMaternal complication ratesMaternal morbidity ratesMaternal obstetric complicationsObstetric complication ratesObstetrics residency programsRetrospective cohort studyNinth Revision codesObstetric complicationsClinical characteristicsCohort studyPatient characteristicsChildbirth outcomesMorbidity ratePreventable complicationsRevision codesIllinois HospitalMorbidityAssociation Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality
Son M, Roy A, Grobman WA, Miller ES. Association Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality. Obstetrics And Gynecology 2018, 132: 365-370. PMID: 29995733, PMCID: PMC6060011, DOI: 10.1097/aog.0000000000002699.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unit admissionIntensive care unit admissionComposite perinatal morbidityCare unit admissionPerinatal morbidityECV attemptWeeks of gestationUnit admissionMortality outcomesNeonatal anemiaLower mean body mass indexMean body mass indexExternal cephalic version attemptNeonatal therapeutic hypothermiaNonanomalous singleton gestationsRetrospective cohort studyTertiary care institutionBody mass indexExternal cephalic versionNonvertex presentationExpectant managementCohort studyFetal malpresentationSecondary outcomesSingleton gestations
2016
Is There an Association Between Indication for Intrauterine Balloon Tamponade and Balloon Failure?
Son M, Einerson BD, Schneider P, Fields IC, Grobman WA, Miller ES. Is There an Association Between Indication for Intrauterine Balloon Tamponade and Balloon Failure? American Journal Of Perinatology 2016, 34: 164-168. PMID: 27367285, DOI: 10.1055/s-0036-1585084.Peer-Reviewed Original ResearchConceptsIntrauterine balloon tamponadeFresh frozen plasmaUterine atonyPostpartum hemorrhageBalloon tamponadeRed blood cellsBalloon placementIntensive care unit admissionCare unit admissionUterine artery embolizationUnit admissionICU admissionSite bleedingArtery embolizationCohort studySecondary outcomesBlood lossPrimary outcomeRBC transfusionPotential confoundersFrozen plasmaMedian EBLBleedingTransfusionAtonyA universal mid-trimester transvaginal cervical length screening program and its associated reduced preterm birth rate
Son M, Grobman WA, Ayala NK, Miller ES. A universal mid-trimester transvaginal cervical length screening program and its associated reduced preterm birth rate. American Journal Of Obstetrics And Gynecology 2016, 214: 365.e1-365.e5. PMID: 26928150, DOI: 10.1016/j.ajog.2015.12.020.Peer-Reviewed Original ResearchConceptsWeeks of gestationTransvaginal cervical lengthUniversal cervical lengthPreterm birth rateUniversal transvaginal cervical lengthPrevious preterm birthCervical length measurementCervical lengthPreterm birthBirth rateTransvaginal cervical length measurementPrevious term birthPreterm birth preventionCervical length assessmentSingle tertiary institutionSpontaneous preterm birthUniversal screening programBreslow-Day testShort cervixSingleton gestationsBirth preventionCohort studyEligible womenMultiparous womenTerm births
2015
Clinical indication and timing of antenatal corticosteroid administration at a single centre
Levin HI, Ananth CV, Benjamin-Boamah C, Siddiq Z, Son M, Friedman AM. Clinical indication and timing of antenatal corticosteroid administration at a single centre. BJOG An International Journal Of Obstetrics & Gynaecology 2015, 123: 409-414. PMID: 26485686, DOI: 10.1111/1471-0528.13730.Peer-Reviewed Original ResearchConceptsAntenatal corticosteroidsMajority of womenPreterm birthACS administrationHypertensive disordersPreterm deliveryGestational ageAdministration of ACSOptimal timingAntenatal corticosteroid administrationPositive fetal fibronectinRetrospective cohort studySpontaneous preterm birthTertiary medical centerUltrasound cervical lengthSingleton preterm birthWeeks gestational ageAntenatal steroidsCervical lengthCorticosteroid administrationPreterm laborSteroid administrationCohort studyFetal fibronectinAsymptomatic women
2014
Preterm Premature Rupture of Membranes and the Rate of Neonatal Sepsis After Two Courses of Antenatal Corticosteroids
Gyamfi-Bannerman C, Son M. Preterm Premature Rupture of Membranes and the Rate of Neonatal Sepsis After Two Courses of Antenatal Corticosteroids. Obstetrics And Gynecology 2014, 124: 999-1003. PMID: 25437730, DOI: 10.1097/aog.0000000000000460.Peer-Reviewed Original ResearchConceptsNeonatal sepsisPreterm premature ruptureCorticosteroid coursesPremature ruptureMaternal-fetal medicine unitRespiratory distress syndromeMultivariable logistic regressionStudent's t-testAntenatal corticosteroidsPreterm PROMSingleton gestationsCohort studyPatient characteristicsDistress syndromePrimary outcomeGestational agePrimary exposureBirth weightMedicine unitSepsisSecondary analysisLogistic regressionCategorical variablesT-testLength of time